Protein Info for HGI48_RS13965 in Dickeya dianthicola 67-19

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 619 PF00078: RVT_1" amino acids 89 to 234 (146 residues), 92 bits, see alignment E=6.5e-30 PF01348: Intron_maturas2" amino acids 394 to 490 (97 residues), 36 bits, see alignment E=9.7e-13 PF21368: AI2M-like_HNH" amino acids 550 to 596 (47 residues), 47.8 bits, see alignment 1.7e-16

Best Hits

Predicted SEED Role

"Retron-type RNA-directed DNA polymerase (EC 2.7.7.49)" (EC 2.7.7.49)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.49

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RF36 at UniProt or InterPro

Protein Sequence (619 amino acids)

>HGI48_RS13965 hypothetical protein (Dickeya dianthicola 67-19)
MLSDTLQRRLESIPVLSKQGKRINGLSRIMTAPKLWLQAYEDIAPNRGATTRGVTSDTLD
GFSLERLTKIIDQVSNGTYRFSPVRRVLIPKANGKTRPLGIPTASDKLVQSVVKIILERI
YEPVFSPKSYGFRRGCSCHDALLDIKHHWTGVKWLIDIDVVSFFDNIDHRVLLALLSRKI
EDKRFLRLINNMLKAGYMEDWKFSATYSGTPQGGVVSPLLANIYLHELDQFLIQGKSQFN
KGERRAENPQYRRLTQRIYQRRRRAEKLLSEGREGDAQVILTSVRCLEEERSVMPSKDGM
DPGYKRLMFCRYADDFLIGVIGSRDEAREMMREVTAFLSENLHLEASQEKSKISKATDGT
IFLGYTVRAITDSRIRRTKLGRRVVRSRDPAGRIHLLVPPERLVRFNQRNGYGDLGRLKA
IHRRHLVDSSLLEIVLAYNAEMRGLANYYRLAYCAKFSLRKLWFLWETSLLKTLAFKLRL
SVNQVAHRLKTRNGLVVRFCIQGKERAVAVFSLKHLNQLPNLGNKVDKLAVPWFTSGRSD
VMDRLLARQCEYCGATGVPCEIHHSRKLADMKDTPLWKQVAAARRRKRIVLCLACHKALH
AGTLKPRNGNGNWQTWRAG