Protein Info for HGI48_RS12260 in Dickeya dianthicola 67-19

Annotation: PAS domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 515 transmembrane" amino acids 169 to 188 (20 residues), see Phobius details amino acids 195 to 213 (19 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 14 to 114 (101 residues), 50.8 bits, see alignment E=8.8e-18 PF13426: PAS_9" amino acids 20 to 106 (87 residues), 46.8 bits, see alignment E=9.6e-16 PF00989: PAS" amino acids 20 to 112 (93 residues), 39.8 bits, see alignment E=1.3e-13 PF08448: PAS_4" amino acids 23 to 112 (90 residues), 23.4 bits, see alignment E=1.8e-08 PF08447: PAS_3" amino acids 30 to 112 (83 residues), 57.1 bits, see alignment E=5.5e-19 PF00672: HAMP" amino acids 214 to 258 (45 residues), 22.3 bits, see alignment 4e-08 PF00015: MCPsignal" amino acids 327 to 483 (157 residues), 162.5 bits, see alignment E=2.7e-51

Best Hits

KEGG orthology group: K03776, aerotaxis receptor (inferred from 96% identity to ddd:Dda3937_00107)

Predicted SEED Role

"Aerotaxis sensor receptor protein" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RE91 at UniProt or InterPro

Protein Sequence (515 amino acids)

>HGI48_RS12260 PAS domain-containing protein (Dickeya dianthicola 67-19)
MRNNQPVTQREYVFDKDATLMSVTDVNSHIVYANDAFIQVSGFEPDEIDGQPHNFVRHPD
MPVEAFRDMWQTLKQQEPWTALVKNRRKNGDHYWVRANAVPIVRQGRTTGYMSVRTQPSR
QEVDAAEALYQSMRRDQGKNLKLHKGVLFRAGLTGLFSRLKLISMRWRLRGLIMLTALIS
YVVFWTIHGNFDADFYISSAFMTGMMLLLDGLLEWQLIKPIEMVKQQALNIATGNVNTID
YGNRADEIGTIQRAIGQLGLMFRWLVDDISTQVLNIRSASDELAHGSEDMSDHAERTAAN
VQQTAAAMNQINTTVQTNTTTTSEASQQAATACDAAISGGRVIGEMEKTMDSIVASSEKI
AGITSIIDNIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRSLAQRSASAANEIKQLI
ESSVEQVRYGSSHVRDAGDSTQNIVTRVNSVSQLISHIADSTKEQTIGLSEIGRAVEELE
QITQKNASQVNACAQASDQLKVQAHRLEQALHVFR