Protein Info for HGI48_RS11475 in Dickeya dianthicola 67-19

Annotation: translation initiation factor IF-3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 180 TIGR00168: translation initiation factor IF-3" amino acids 15 to 179 (165 residues), 252.1 bits, see alignment E=9.9e-80 PF05198: IF3_N" amino acids 15 to 84 (70 residues), 117.4 bits, see alignment E=2.5e-38 PF00707: IF3_C" amino acids 91 to 177 (87 residues), 122.3 bits, see alignment E=6.3e-40

Best Hits

Swiss-Prot: 97% identical to IF3_PECCP: Translation initiation factor IF-3 (infC) from Pectobacterium carotovorum subsp. carotovorum (strain PC1)

KEGG orthology group: K02520, translation initiation factor IF-3 (inferred from 92% identity to eco:b1718)

Predicted SEED Role

"Translation initiation factor 3"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RJG1 at UniProt or InterPro

Protein Sequence (180 amino acids)

>HGI48_RS11475 translation initiation factor IF-3 (Dickeya dianthicola 67-19)
MKGGKRVQPARPNRINREIRAQEVRLTGVDGEQIGIVSLNEALEKAEEAGVDLVEISPNA
EPPVCRIMDYGKFLYEKSKSTKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLVRFLED
GDKAKITLRFRGREMAHQQIGIEVLNRVRDDLSELAVVESFPTKIEGRQMIMVLAPKKKQ