Protein Info for HGI48_RS11100 in Dickeya dianthicola 67-19

Annotation: exodeoxyribonuclease V subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1227 TIGR00609: exodeoxyribonuclease V, beta subunit" amino acids 10 to 1219 (1210 residues), 1056.9 bits, see alignment E=0 PF00580: UvrD-helicase" amino acids 17 to 455 (439 residues), 164.9 bits, see alignment E=8.2e-52 PF13245: AAA_19" amino acids 22 to 442 (421 residues), 41.8 bits, see alignment E=2.9e-14 PF13361: UvrD_C" amino acids 762 to 850 (89 residues), 49.8 bits, see alignment 8.9e-17 PF12705: PDDEXK_1" amino acids 992 to 1206 (215 residues), 33.3 bits, see alignment E=1.3e-11

Best Hits

KEGG orthology group: K03582, exodeoxyribonuclease V beta subunit [EC: 3.1.11.5] (inferred from 94% identity to ddd:Dda3937_02948)

Predicted SEED Role

"Exodeoxyribonuclease V beta chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RDL9 at UniProt or InterPro

Protein Sequence (1227 amino acids)

>HGI48_RS11100 exodeoxyribonuclease V subunit beta (Dickeya dianthicola 67-19)
MTAHSLPSPLDVLRFPLAGSRLIEASAGTGKTFTIAMLYVRLVLGHGGEQAFSRPLNPPD
ILVVTFTDAATRELRDRIRARLAQAAGYFQPDGKDDKEDEADPLLRALRADYPPEQWPAC
ARKLQLAAEWMDEAAVSTIHGWCNRMLGEHAFDSGSLFNQTLETDQSDVLLEVVRDYWRT
FFFPLDARDVLELRDSWPSPEHFYRSVTPLLEYADEIGIDDLPAQIFSAVREEKTCRLAA
LKAPWPQWCGELRDVLNAAVAQKKADGRKLQARYFESWLDKLHLWATSDETTLDIGTGWT
RLTPQGLRECWKVPEETPQHPALTAMEALQQQLSDLPEPRSHLLRHACRWVSRRFRHEQE
SRAQMGFQDLLTRLDAALRGDNGERLAQRIRRQFPVAMIDEFQDTDPLQYRIFDTLYRVA
DNDPQQGLILIGDPKQAIYAFRGADIYTYLRARRDTDGRHYTLGTNFRSTQAMVGAVNQV
FMQAENRADGAGAFLFRQPDGGNPVPFLPVQANGRDEAWILEGADAAALTCWTLATDEPL
SSAEYRQRMAAGCAREMVRLLQLGGQGRAGFAVPGQALRPVRPGDMAVLVNTGREAMAVR
AQLSARGVRSVYLSDRESVFDSPQAGELHCWLAACADPENDRLLRAALGTPLLGLSWQAL
DRLNHDEQEWERRVMQFVRYQSCWRQQGVLPMLRRLMWEFEVPRRLLAADNARALTDVLH
LSELLQQASVHLDGEHALIRYLAEQCQADNPGGDTLKLRLESDADLVKVVTVHKSKGLEY
PLVFLPFACAFRAVNQRDVPLKYHDDDGQPRLELTVSDEAVQRADHERLGEDLRKFYVAL
TRARYALWLGMAPLKDLEKSAPGYLLGAGEPLEPAQLAQPLSAWCGAHSQMAPLPETDDE
VYRAELNAPALGQEPPLPDMRRHRWRITSYSGLQLAPEGHYREFREPSAGDVPEVQSAQQ
ETFSEPQASVERLPPLPAGLDMYSFPRGAAPGSFLHGLLEWAGKEGFAALAAERPRVEDQ
VARRCNRQGWTQWIPMLTDWLMALLSQPLALPTSPGSAVSLAGLTQYQVEMEFWFALNQV
DTQVLDQQVRAATLAGEPRAALMREQLNGMLKGFIDLVFEHQGRYYVLDYKSNWLGADVA
DYDPARMAHAMLDHRYDLQLALYLFALHRLLKSRLPDYDYDRHVGGALYLFLRGSQAPGG
GVFAQRPDRALIEALDRLFSGETEATA