Protein Info for HGI48_RS11095 in Dickeya dianthicola 67-19

Annotation: exodeoxyribonuclease V subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 681 TIGR01447: exodeoxyribonuclease V, alpha subunit" amino acids 13 to 678 (666 residues), 578.4 bits, see alignment E=9.1e-178 PF21185: RecD_N" amino acids 15 to 131 (117 residues), 52.4 bits, see alignment E=2.4e-17 PF13245: AAA_19" amino acids 184 to 342 (159 residues), 113.1 bits, see alignment E=4.9e-36 PF13604: AAA_30" amino acids 188 to 361 (174 residues), 88.2 bits, see alignment E=2.8e-28 PF13401: AAA_22" amino acids 195 to 323 (129 residues), 27.9 bits, see alignment E=1.2e-09 PF05127: Helicase_RecD" amino acids 198 to 324 (127 residues), 30.2 bits, see alignment E=1.9e-10 PF13538: UvrD_C_2" amino acids 609 to 652 (44 residues), 41.8 bits, see alignment 3.5e-14

Best Hits

KEGG orthology group: K03581, exodeoxyribonuclease V alpha subunit [EC: 3.1.11.5] (inferred from 95% identity to ddd:Dda3937_02949)

Predicted SEED Role

"Exodeoxyribonuclease V alpha chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RE06 at UniProt or InterPro

Protein Sequence (681 amino acids)

>HGI48_RS11095 exodeoxyribonuclease V subunit alpha (Dickeya dianthicola 67-19)
MNMTRHDDVTQLLDQWVGCGWLRELDRALVRFLHQECPDAPPLLLLGAALVSYQLGRGHV
CLDLAATLADSGFSLALPPEGDRSENRKIARPAAVLAGVTLSAWQAALQQPQLVSSGEGS
TPLVLVGARLYLRRYWRYEQDVRHAITQQLTQNHALRAAIAPAVLRQRLDALFPTAAAGP
ANWQKLACALAAGSAFSIITGGPGTGKTTTVVKLLALLQSLALEQHGKPLRIRLAAPTGK
AAARLNESIAGAIAGLMLDGLAQGEAIREHINSEVVTLHRLLGSRPDTRHFRHHADNPLM
LDVLVVDEASMVDLEMMAALLAAMPARSRLILLGDKDQLASVEAGALMGELCQRAAQGHY
LPQTRDWLREVAGDAPDDALLDPHGSALDQSIAMLRHSYRFGADSGIGQLAEAVNAGDAA
ALAAVWQHGYADLARLTLTANDNRALREWVIDGAVDRFACQPHAAPPVGYGDYLRRMAST
RPALTAAQSEFDVWAAQILDAFGQFQLLCALRNGPWGVDSMNERIAHLLYRDGLLAAWQG
WYPGRPVMVTRNDYSQRLMNGDIGITLPVPLLQPDGSRAWVTRVAFPAGDGSSGIRWVLP
GRLSAVETVFAMTVHKSQGSEFAHTALLLPDCLSPILTRELVYTGITRAKHAFSLGCVGE
HSTVLAEAVGRRVLRVSGRFP