Protein Info for HGI48_RS10660 in Dickeya dianthicola 67-19

Annotation: DNA replication terminus site-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 PF05472: Ter" amino acids 9 to 303 (295 residues), 451.9 bits, see alignment E=4.3e-140 TIGR02648: DNA replication terminus site-binding protein" amino acids 10 to 305 (296 residues), 498 bits, see alignment E=4.6e-154

Best Hits

Swiss-Prot: 60% identical to TUS_YERE8: DNA replication terminus site-binding protein (tus) from Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)

KEGG orthology group: K10748, DNA replication terminus site-binding protein (inferred from 95% identity to ddd:Dda3937_04127)

Predicted SEED Role

"DNA replication terminus site-binding protein" in subsystem DNA-replication

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RDJ8 at UniProt or InterPro

Protein Sequence (308 amino acids)

>HGI48_RS10660 DNA replication terminus site-binding protein (Dickeya dianthicola 67-19)
MAAYDLIERMNHCFTTLEAQLAEMHQLFRAFRFAGGHIFSLPPVEKGTEHDPVTHIHVTP
VTGDDARDTGLQHFRHLFIHHHAETVSSKAAIRLPGVLCFRVEQPEYLQAHRLITDINAR
KNELEQIITVESGLEPEQRFDFVHTHLKGLITLSAYRTLTLLVDPTSVRFGWANKNIIKN
LTRDDLLEKLEKSLHAGRSQAPYSKEQWASLLEQEIQDVKRLPEQASLKIKRPVKVQPIA
RVWYQEQQKQVQYPCPSPLLVLCRQDTVPVMGALNDYDADNIQHRHRPKAKPLRLLIPRL
HLYTDDGI