Protein Info for HGI48_RS10220 in Dickeya dianthicola 67-19

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 371 PF02518: HATPase_c" amino acids 248 to 360 (113 residues), 80.4 bits, see alignment E=6.7e-27

Best Hits

KEGG orthology group: None (inferred from 91% identity to ddd:Dda3937_03320)

Predicted SEED Role

"Signal transduction histidine kinase HoxJ (hydrogenase regulation)" in subsystem Hydrogenases or Membrane-bound Ni, Fe-hydrogenase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RJF6 at UniProt or InterPro

Protein Sequence (371 amino acids)

>HGI48_RS10220 sensor histidine kinase (Dickeya dianthicola 67-19)
MTEGTFSEASVMDLSAAEYQRKLAARDKTIDVLKRRIAQEARHSHATPFAILEQTVGLEK
VVARKTLELENERQELEKALTELRFTQAQLLQAQKMESIGQLAAGIAHEINTPTQYVSDN
VGFVKTATVSLLSLLDSALALAEATRGKMDAEPVVAEFDAALKRTKVDFLRRQIPSALDE
SLEGLGHIAKIVAAMKEFSHPSHNEKEMVDVREVINTTVTVARNEWKYVAELETHFEDDL
PQLPCLRDMIGQAILNLVVNAAHAITDTIQEGVKEKGHIIVSAAQRGEHMEIRVKDDGSG
IPAGIRDRIFDPFFTTKAVGKGTGQGLAIVYSTVVDKHDGLIRCESEEGVGTTFILQLPL
HCRKEDCPACK