Protein Info for HGI48_RS10015 in Dickeya dianthicola 67-19

Annotation: Gfo/Idh/MocA family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 307 PF01408: GFO_IDH_MocA" amino acids 4 to 121 (118 residues), 105.6 bits, see alignment E=2.7e-34 PF21378: YceM-like_C" amino acids 127 to 249 (123 residues), 137.3 bits, see alignment E=3.1e-44

Best Hits

Swiss-Prot: 61% identical to YCEM_SALTY: Putative oxidoreductase YceM (yceM) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K03810, virulence factor (inferred from 94% identity to ddd:Dda3937_04329)

Predicted SEED Role

"Virulence factor MviM" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RD42 at UniProt or InterPro

Protein Sequence (307 amino acids)

>HGI48_RS10015 Gfo/Idh/MocA family oxidoreductase (Dickeya dianthicola 67-19)
MKSLRIGVVGLGDIARKAYLPILSQAEHWQLAGAWSPGQARARQLCQQYRIACFSSLEAL
SSQCDAVFVHSSTASHYEVVKTLLLAGKHVYVDKPLAETLAQAEELVALAASRNLLLMVG
FNRRFAPLYQRLRQLRPFPDSLRMEKHRIDNIGPHPLAFTLLDDYLHVVDTALWLAETPD
APAMLCGGLLRCNPQGQLIYAEHQFQSAHGMITTSMHRQAGSQRESVQLVNEGGGYQVDN
LREWREERDGTVLLHPAPSWQSTLEQRGFVGAVRHFIDAVVSHTPPLTSGDQALRAQRVI
EMLLRKR