Protein Info for HGI48_RS09670 in Dickeya dianthicola 67-19

Annotation: formate transporter FocA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 285 transmembrane" amino acids 33 to 55 (23 residues), see Phobius details amino acids 69 to 98 (30 residues), see Phobius details amino acids 115 to 136 (22 residues), see Phobius details amino acids 161 to 181 (21 residues), see Phobius details amino acids 192 to 215 (24 residues), see Phobius details amino acids 255 to 278 (24 residues), see Phobius details TIGR04060: formate transporter FocA" amino acids 14 to 279 (266 residues), 406.6 bits, see alignment E=4e-126 PF01226: Form_Nir_trans" amino acids 15 to 276 (262 residues), 255.1 bits, see alignment E=3.1e-80 TIGR00790: formate/nitrite transporter" amino acids 26 to 280 (255 residues), 304.5 bits, see alignment E=5.5e-95

Best Hits

Swiss-Prot: 78% identical to FOCA_ECO57: Probable formate transporter 1 (focA) from Escherichia coli O157:H7

KEGG orthology group: K06212, formate transporter (inferred from 95% identity to ddd:Dda3937_03349)

MetaCyc: 78% identical to formate channel FocA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-1; TRANS-RXN-381

Predicted SEED Role

"Formate efflux transporter (TC 2.A.44 family)" in subsystem Fermentations: Mixed acid

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RCY2 at UniProt or InterPro

Protein Sequence (285 amino acids)

>HGI48_RS09670 formate transporter FocA (Dickeya dianthicola 67-19)
MKADNPFTLLLPSAMAKVAEDAGVYKATKQPLTAFFLAITAGVFISAAFVFYITATTGSS
SMPYGMAKLVGGICFSMGLMLVVVCGADLFTSTVLTVIAKASGRITWKQLGMNWLNVYVG
NLIGALFFVALIWFSGEFMVANGAWGLNVLQTASHKLEHSFVEALCLGILANLMVCLAIW
MSYSGHTLTDKMLAMILPVAMFVASGFEHSIANMFMVPMGVVIKDFAPDAFWHAISMTPG
QFEHLTVSNFIVDNLIPVTIGNIIGGGLLVGLTYWAIYLRGGDQH