Protein Info for HGI48_RS09610 in Dickeya dianthicola 67-19

Annotation: DNA translocase FtsK 4TM domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1199 transmembrane" amino acids 22 to 44 (23 residues), see Phobius details amino acids 75 to 97 (23 residues), see Phobius details amino acids 109 to 131 (23 residues), see Phobius details amino acids 137 to 155 (19 residues), see Phobius details amino acids 163 to 184 (22 residues), see Phobius details PF13491: FtsK_4TM" amino acids 20 to 191 (172 residues), 157.6 bits, see alignment E=4.9e-50 PF17854: FtsK_alpha" amino acids 709 to 809 (101 residues), 101.7 bits, see alignment E=4.6e-33 PF01580: FtsK_SpoIIIE" amino acids 817 to 1030 (214 residues), 280.1 bits, see alignment E=2.3e-87 PF09397: FtsK_gamma" amino acids 1134 to 1194 (61 residues), 93.1 bits, see alignment 1.4e-30

Best Hits

Predicted SEED Role

"Cell division protein FtsK" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Bacterial RNA-metabolizing Zn-dependent hydrolases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RD97 at UniProt or InterPro

Protein Sequence (1199 amino acids)

>HGI48_RS09610 DNA translocase FtsK 4TM domain-containing protein (Dickeya dianthicola 67-19)
MSQEYTEDKDVTLKKLSAGRRLLEAMLIVVVLFAIYLAVALLSFSPSDPSWSQTAWHEPI
HNLGGGVGAWLADTLFFIFGVLAYAIPVVMASLCWVIHRQRGQRATLDYFALSLRLIGTL
ALILTSCGLAALNVDDIYYFASGGVLGSLLSSSMVPRFNNIGATMILLCVWAAGLTLFTG
WSWLTIAEKLGAGVMGCLTLFSGRRREDNYLYDDDDDDDDIDESSAAARKDAHRTAAPHD
DEPAAVSSAVSVSSSVSVSSSVVVSSAAEVDNDDDDALFSAPGVTATSGAVAVEMPVVNQ
ANARAFATTATPDAEPVLKPHPEPIAVTPLAGPESFVPPVAAPVPEFRPGADVSPVSPLA
PAPEGIVPAGIVPASADFAPSLSEPLPDWQPLTLQADDRIARTAAAAVTAATVVAGNAGA
VTEPKPESQNATPFMPAFTTDEDNNPQVKRGMGPELPRPNPVRIPTRRELASYGIKLPSQ
RLAEQQAREAEQQAQSALVEPTGALTPFAAQTPLPDMPDDETAQTALPDDEQDTLIQEAA
LRQAFADQQRERYGETYPDHEEAEDTLLQAQLARDFAAMQRSRYTAHGPDTEQDAPAIFA
AESPAVTPAAAETTAFGMKPRADDPLDSAFAISPFADLVEDGPLEPLFTLPPQESFPDEP
QYAPAPALQTAAPTEPEAEAESSSSMMDSLIHPFLMRNDQPLHKPTTPLPSLDLLTPPSM
NDAPVDRDVLDDMARLIETRLADYRVKATVVDYHPGPVITRFELDLAPGVKAARISNLAR
DLARSLSVVAVRIVEVIPGKPYVGLELPNRHRQTVFLREVLDCDRFRDNASPLAIVLGKD
ISGQPVVADLAKMPHLLVAGTTGSGKSVGVNAMIISMLYKATPADVRFIMIDPKMLELSV
YEGIPHLLTEVVTDMKDAANALRWCVGEMERRYKLMSALGVRNLSGYNERVMQAEAMGRP
VPDPFWKPGDSMDAQPPVLEKLPYIVVMVDEFADLMMAVGKKVEELIARLAQKARAAGIH
LVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQGGAESLLGMGDMLYMAPNS
SIPIRVHGAFVRDQEVHAVVQDWKARGRPEYIDNIISGDDDGEGGSLGFDGDEDLDPLFD
QAVAFVVEKRRASISGVQRQFRIGYNRAARIVEQMEMQGIVSSPGHNGNREVLAPPPME