Protein Info for HGI48_RS08670 in Dickeya dianthicola 67-19

Annotation: adenosylmethionine--8-amino-7-oxononanoate transaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 TIGR00508: adenosylmethionine-8-amino-7-oxononanoate transaminase" amino acids 13 to 421 (409 residues), 611.2 bits, see alignment E=3.9e-188 PF00202: Aminotran_3" amino acids 28 to 421 (394 residues), 420.7 bits, see alignment E=2.7e-130

Best Hits

Swiss-Prot: 76% identical to BIOA_ESCVU: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (bioA) from Escherichia vulneris

KEGG orthology group: K00833, adenosylmethionine-8-amino-7-oxononanoate aminotransferase [EC: 2.6.1.62] (inferred from 95% identity to ddd:Dda3937_03747)

MetaCyc: 75% identical to adenosylmethionine-8-amino-7-oxononanoate aminotransferase (Escherichia coli K-12 substr. MG1655)
Adenosylmethionine--8-amino-7-oxononanoate transaminase. [EC: 2.6.1.62]

Predicted SEED Role

"Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)" in subsystem Biotin biosynthesis (EC 2.6.1.62)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.62

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RCT7 at UniProt or InterPro

Protein Sequence (427 amino acids)

>HGI48_RS08670 adenosylmethionine--8-amino-7-oxononanoate transaminase (Dickeya dianthicola 67-19)
MTQDDLTFDQRHIWHPYTSMTAPLPCYPVIAANGCRLRLADGRQLVDGMSSWWAAIHGYN
HPRLNQALTDQLAQMSHVMFGGITHPAAVALCRQLVAITPAALECVFLADSGSVAVEVAM
KMALQYWQARGERRQRFLTLRHGYHGDTFGAMSVCDPENSMHSLYQGYLPPHLFADAPRG
GVDQPWQPEDITPFSALLRQHQHQIAAVILEPVVQGAGGMRFYHPEYLRQVRRLCDQHGI
LLIADEIATGFGRTGRLFACEHAGVTPDILCLGKALTGGYMTLSATLTTRTVADTISNGE
AGCFMHGPTFMGNPLACAVAHANLTLLAENRWQAQVAAIEAQLRQALLPLREAPTVADVR
VLGAIGVVETRRPVDMARLQRFFVDQGVWIRPFGKLIYLMPPFIIQPEELQALTDAVRQA
VFTPALW