Protein Info for HGI48_RS08555 in Dickeya dianthicola 67-19

Annotation: helix-turn-helix domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 81 PF13693: HTH_35" amino acids 5 to 73 (69 residues), 114.5 bits, see alignment E=9.3e-38

Best Hits

Swiss-Prot: 54% identical to NER_BPD10: Negative regulator of transcription (ner) from Escherichia phage D108

KEGG orthology group: K07724, Ner family transcriptional regulator (inferred from 98% identity to dze:Dd1591_1156)

Predicted SEED Role

"Ner-like regulatory protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RCE4 at UniProt or InterPro

Protein Sequence (81 amino acids)

>HGI48_RS08555 helix-turn-helix domain-containing protein (Dickeya dianthicola 67-19)
MEQHDWHPADIIAGLRKRGTTLAAVSREAGLASSTLANTLVRHWPKGERLIANALNKRPE
EIWPSRYHDLKRTPNGEGKSE