Protein Info for HGI48_RS08235 in Dickeya dianthicola 67-19

Annotation: starvation-sensing protein RspA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 417 PF02746: MR_MLE_N" amino acids 19 to 115 (97 residues), 75 bits, see alignment E=6e-25 PF13378: MR_MLE_C" amino acids 206 to 389 (184 residues), 142.6 bits, see alignment E=1.6e-45

Best Hits

Swiss-Prot: 98% identical to DGD_SALVI: D-galactonate dehydratase family member SeV_A0456 (SeV_A0456) from Salmonella virchow

KEGG orthology group: K08323, starvation sensing protein RspA (inferred from 97% identity to seg:SG1503)

Predicted SEED Role

"Starvation sensing protein RspA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RCB5 at UniProt or InterPro

Protein Sequence (417 amino acids)

>HGI48_RS08235 starvation-sensing protein RspA (Dickeya dianthicola 67-19)
MSNLKITNVKTILTAPGGIDLAVVKVETNEPGLYGLGCATFTQRIFAVKSAIDEYMAPFL
IGKDPTRIEDIWQSGAVSGYWRNGPIMNNALSGVDMALWDIKGKLAGMPVYDLLGGKCRD
GIPLYCHTDGGDEVEVEDNIRARMEEGYQYVRCQMGMYGGAGTDDLKLIATQLARAKNIQ
PKRSPRSKTSGIYFDPDAYAKSVPRLFDHLRNKLGFDIEFIHDVHERVTPVTAINLAKTL
EQFQLFYLEDPVAPENIDWLKMLRQQSSTPISMGELFVNVNEWKPLIDNKLIDYIRCHVS
TIGGITPAKKLAVYSELNGVRTAWHGPGDISPVGVCANMHLDLSSPNFGIQEYTPMNDAL
RDVFPGCPEIDRGYAYLNDKPGLGIDLDEVKAAKYPCEGGIPSWTMARTPDGTASRP