Protein Info for HGI48_RS07065 in Dickeya dianthicola 67-19

Annotation: SIR2 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 396 transmembrane" amino acids 23 to 39 (17 residues), see Phobius details PF13289: SIR2_2" amino acids 174 to 331 (158 residues), 80.4 bits, see alignment E=6.9e-27

Best Hits

KEGG orthology group: None (inferred from 81% identity to dps:DP1918)

Predicted SEED Role

"FIG036446: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RBP7 at UniProt or InterPro

Protein Sequence (396 amino acids)

>HGI48_RS07065 SIR2 family protein (Dickeya dianthicola 67-19)
MEEFDNRLENIKQLLSSQSRQSWLFGAGISFGSKIPLMYPLTSRVERIIEENSEDKEKEI
LAVLKADLSDDCHVEHYLSHLGDLLAIADRSRNQSAYIGTNSYTSEELRRLYLEIIKAIG
GIIRYGYVAANAERAIEEEIGSAANPIVEIEPHYKFIEALLISKSNLEQRSKTTFFTTNY
DTLLEDALALHKKIVCDGFSGGAVGFWNAENAFSNAAIDSNTYHLYKLHGSIDWHRDDDL
GLVRARYGTKYLSNPANIMIYPQATKYVETQKDPFANLFLGLRKTLMSGQQNTLITCGYS
FGDDHINSEIESALRSESNQTTVIAFVQESPKGVIVINKTLDAWLRCPKISSRVYVAGEL
GIYHNSTTPLAESDVSKYAWWRFDGLTQFISTGEVS