Protein Info for HGI48_RS06455 in Dickeya dianthicola 67-19

Annotation: type 2 GTP cyclohydrolase I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 247 TIGR00486: dinuclear metal center protein, YbgI/SA1388 family" amino acids 1 to 246 (246 residues), 230.4 bits, see alignment E=1.3e-72 PF01784: DUF34_NIF3" amino acids 6 to 233 (228 residues), 202.3 bits, see alignment E=5.1e-64

Best Hits

Swiss-Prot: 75% identical to GCH1L_YERPE: GTP cyclohydrolase 1 type 2 homolog (YPO2697) from Yersinia pestis

KEGG orthology group: None (inferred from 95% identity to ddd:Dda3937_01545)

Predicted SEED Role

"FIG137478: Hypothetical protein YbgI"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RBE8 at UniProt or InterPro

Protein Sequence (247 amino acids)

>HGI48_RS06455 type 2 GTP cyclohydrolase I (Dickeya dianthicola 67-19)
MRNTELESLINGFLNVAAFQDYGPNGLQVEGRREVRRIVTGVTACQALLDAAVAQQADAV
LVHHGYFWRNEPAVVRGMKRQRLKTLLANDLNLYGYHLPLDAHPEVGNNARLAAMLGIRA
LGEIESLLPYGELAQPCSGDDLRQTLEAVLARPVLHSGDNAPAQIRRIAWCTGGGQGFID
QAADFGVDAFITGEVSEKTIHTAREMGLHFYAAGHHATERAGIRALGEWLASQHGFDVTF
IDIPNPA