Protein Info for HGI48_RS05875 in Dickeya dianthicola 67-19

Annotation: glycoside hydrolase family 28 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF12708: Pectate_lyase_3" amino acids 33 to 207 (175 residues), 27 bits, see alignment E=5.5e-10 PF00295: Glyco_hydro_28" amino acids 61 to 338 (278 residues), 176.4 bits, see alignment E=1.3e-55 PF13229: Beta_helix" amino acids 171 to 304 (134 residues), 32.2 bits, see alignment E=1.3e-11

Best Hits

KEGG orthology group: None (inferred from 96% identity to ddd:Dda3937_04155)

Predicted SEED Role

"Polygalacturonase (EC 3.2.1.15)" in subsystem D-Galacturonate and D-Glucuronate Utilization (EC 3.2.1.15)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RBF6 at UniProt or InterPro

Protein Sequence (457 amino acids)

>HGI48_RS05875 glycoside hydrolase family 28 protein (Dickeya dianthicola 67-19)
MHKGIAFSLLASCALAGMAAQAAEKVAFPDRVCNVTGYGAEGHRLQIALNTASFQKAIDD
CAAAGGGTVLVPAGNYLVEPLFLKSNVRLHLEKNATLVASTGENAYRATDSTRYAEAENG
WLPFISIADAQNVAITGEGTIDGQGAVWWERWRTAIRATGKKGGTDRPRLIYVTRSSQVL
IDGVTLTNSPSFHVVMRYAHDVTVNGTHIIAPWHAPNTDAIDPIDSQNIRITNNVIDCND
DHIAIKAEKPDSRFPNGVVDNIYIANNVLKQGRGISIGSETSGGVNNVLVENNRFEGSMY
GIRIKSPRGKGGEVKNVTYRHTRMVDVEVPLVFSGYYQAAPIVQAEVDKLLQAGGFTLGE
QIYPPDTEPAQPFDKVKTPHFSQVTVVDLESTGRSKAAGYIIGVPEAPLSGFHFEQVRID
AEQGLRVRNAELATNGLTLNAKQGDALLLDKGANVTR