Protein Info for HGI48_RS05440 in Dickeya dianthicola 67-19

Annotation: 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 366 PF01717: Meth_synt_2" amino acids 15 to 359 (345 residues), 68.2 bits, see alignment E=4.1e-23

Best Hits

KEGG orthology group: None (inferred from 92% identity to ddd:Dda3937_01929)

Predicted SEED Role

"Methionine synthase II (cobalamin-independent)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RAX5 at UniProt or InterPro

Protein Sequence (366 amino acids)

>HGI48_RS05440 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (Dickeya dianthicola 67-19)
MRTVKKPYPPFHAEHVGSFLLPPRLKQARQAWRQGLITHDRLTEIENEEVLNVVERQKAC
GLSAITDGELRIHDGITDFFSCLTGIDVDYAALPDGDTPGRLRVMGKLDFDDAHPFLTHY
RFLHQAVGDSSETLAKQTLPSPTMLMYPAIRNNDVYPSLDAFCDDLVAVYRKLIQAFYRQ
GCRYLQLDDLFWARLCDGQVMERENAAGFELRELLARCARTLNQALAQRPPDMFVSLHIC
CRRFSPNWVYGSGREVMGYAMANLAVDSLFIEYDDRRPVGLEPLRQVSCQKVVLGVVDAR
SATLETPDSVKMAINTASLYVPLQQLAISPKCGFRHCGKDDITEEQQWAKLRHMVNIARE
VWTLPE