Protein Info for HGI48_RS03935 in Dickeya dianthicola 67-19

Annotation: conjugal transfer protein TraG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 665 transmembrane" amino acids 7 to 29 (23 residues), see Phobius details amino acids 70 to 94 (25 residues), see Phobius details PF02534: T4SS-DNA_transf" amino acids 112 to 557 (446 residues), 344.5 bits, see alignment E=1.6e-106 PF10412: TrwB_AAD_bind" amino acids 196 to 539 (344 residues), 100.3 bits, see alignment E=1.7e-32 PF12696: TraG-D_C" amino acids 404 to 524 (121 residues), 98.4 bits, see alignment E=4.6e-32

Best Hits

KEGG orthology group: K03205, type IV secretion system protein VirD4 (inferred from 90% identity to rso:RSc2586)

Predicted SEED Role

"Type IV secretion system protein VirD4" in subsystem Type 4 secretion and conjugative transfer or pVir Plasmid of Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RA84 at UniProt or InterPro

Protein Sequence (665 amino acids)

>HGI48_RS03935 conjugal transfer protein TraG (Dickeya dianthicola 67-19)
MQSQGVLFGQIAAVFGIVIAGVWSATQWTAAALGYQLRLGSPWFDFFGTPIYRPWDLFPW
WFSFDAYAPHIFDIGGAIAGGSGLVAVVVAIAMSVWRSRQSRLVTTYGSARWADADDVRK
AGLTQPAGVFLGLHRGQYLRHEGPEHVLTFAPTRSGKGVGLVVPTLLSWPASVVVHDIKG
ENWTLTAGWRSRFSHCLLFNPTDAKSAAYNPLLEVRRGAHEVRDVQNVADILVDPDGALE
RRNHWEKTSHALLVGAILHVLYAGEDKTLRGVANFLSDPACPFELTLHRMMTTKHLGDLP
HPVVASAAREVLNKSDNERSGVLSTAMSFLGLYRDPTVAEVTSRCDWRIADLISAEHPVS
LYLVVPPSDISRTKPLIRLILNQIGRRLTESLDGSDGIARRHKLLLMLDEFPALGRLDFF
ESALAFMAGYGIRSFLIAQSLNQIDKAYGQNHSILDNCHVRVTFATNDERTAKRISETLG
TATELRAQRNYAGHRLAPWLGHLMVSRQETARPLLTPGEVMQLPPDESVVMVSSVAPIKA
KKLRYYTDANFKQRVVAPPTLAVGRYADAPPSRPDDWSGLAIPAVPTAPTTASADDLGGT
DDGGPRRQPELSEVTEYSPEPQPVGNDLGLLDDDDLPLPLPRQFDPAIQRTARLASLDPN
DGIDL