Protein Info for HGI48_RS03880 in Dickeya dianthicola 67-19

Annotation: TrbI/VirB10 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 transmembrane" amino acids 40 to 59 (20 residues), see Phobius details PF03743: TrbI" amino acids 233 to 413 (181 residues), 203 bits, see alignment E=2e-64

Best Hits

KEGG orthology group: K03195, type IV secretion system protein VirB10 (inferred from 91% identity to bmj:BMULJ_00882)

Predicted SEED Role

"Conjugative transfer protein TrbI" in subsystem Type 4 secretion and conjugative transfer

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RA41 at UniProt or InterPro

Protein Sequence (427 amino acids)

>HGI48_RS03880 TrbI/VirB10 family protein (Dickeya dianthicola 67-19)
MSQDDTPDLAVPQAADKIAPEAVALRAQPRPVTRLNRRTLAILAGGLSVAVLGALMWSLQ
PQRRGTGEQTELYNVERVSKSEGLDTLPADYSKLPPPLSPKVPELGPPLPGDLGPAIVRS
QQPVTATYTPPGHDQNDALRKEAESAAASSVFFRSGTQKAAPVAQSQVAAAPGFAANAPF
DPMAAGPASTAAQPADPTAVQNRQDQKEAFQKAGTTETRNSGNLTLPASPYQVMAGTVVA
GALVTGIKSDLPGDVIATVTEPVYDTATGKFLLIPQGSRIQGKYNSQVAYGQSRVQVVWS
RIILPDTSSLTLDNLAGTDPAGYVGLEDDVDWHWDRVFAGAALTTLLGIGAELAAPENRQ
DGDRVIIAGRDSLQDSVNQAGQEMTRRNMNIQPTLTERPGLPVRIIVNRDLTLRPYQPLF
FNRGTSR