Protein Info for HGI48_RS03170 in Dickeya dianthicola 67-19

Annotation: DMT family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 314 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 39 to 59 (21 residues), see Phobius details amino acids 71 to 91 (21 residues), see Phobius details amino acids 102 to 120 (19 residues), see Phobius details amino acids 129 to 148 (20 residues), see Phobius details amino acids 157 to 177 (21 residues), see Phobius details amino acids 189 to 209 (21 residues), see Phobius details amino acids 217 to 236 (20 residues), see Phobius details amino acids 248 to 272 (25 residues), see Phobius details amino acids 282 to 304 (23 residues), see Phobius details PF00892: EamA" amino acids 7 to 142 (136 residues), 88.4 bits, see alignment E=2.4e-29 amino acids 159 to 290 (132 residues), 52.6 bits, see alignment E=2.7e-18

Best Hits

Swiss-Prot: 75% identical to YHBE_ECOLI: Uncharacterized inner membrane transporter YhbE (yhbE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 96% identity to ddd:Dda3937_02353)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9R9S8 at UniProt or InterPro

Protein Sequence (314 amino acids)

>HGI48_RS03170 DMT family transporter (Dickeya dianthicola 67-19)
MKQNAVIGFCLALTTAICWGALPIAMKQVLVTMEPYTIVWYRFLIASVGLGIFLYSKGAL
PTSQAFDHQRWWILLLIATGGLLGNFVLFSSSLQYLSPTASQVIGQLSTVGLMVASVVIL
KEKMRPSQIIGAGVLICGLLMFFNNSLVELFTRLTDYTFGILLGVAASTVWVAYGVAQKV
LLRRLTSQQLLFLLYTLCVLFITPLAKPGVIFQLTSWQLACLLFCGANTLVGYGALAEAM
ARWQAAQVSTIITLTPLFTLFFSDLLALAWPAVFAAPALDLLGYVGAFVVVTGAMFSAVG
HRLIALKRDKRPMV