Protein Info for HGI48_RS01735 in Dickeya dianthicola 67-19
Annotation: L-rhamnose isomerase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 83% identical to RHAA_TOLAT: L-rhamnose isomerase (rhaA) from Tolumonas auensis (strain DSM 9187 / TA4)
KEGG orthology group: K01813, L-rhamnose isomerase [EC: 5.3.1.14] (inferred from 83% identity to tau:Tola_1042)MetaCyc: 75% identical to L-rhamnose isomerase (Escherichia coli K-12 substr. MG1655)
L-rhamnose isomerase. [EC: 5.3.1.14]; 5.1.3.- [EC: 5.3.1.14]
Predicted SEED Role
"L-rhamnose isomerase (EC 5.3.1.14)" in subsystem L-rhamnose utilization (EC 5.3.1.14)
MetaCyc Pathways
- L-rhamnose degradation I (5/5 steps found)
- superpathway of fucose and rhamnose degradation (8/12 steps found)
- L-lyxose degradation (2/4 steps found)
- superpathway of pentose and pentitol degradation (12/42 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 5.3.1.14
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A7L9R922 at UniProt or InterPro
Protein Sequence (419 amino acids)
>HGI48_RS01735 L-rhamnose isomerase (Dickeya dianthicola 67-19) MNPNIETAFTLARQQYAALGVDVDQALATLATIPVSMHCWQGDDVQGFEVNAGALTGGIQ ATGNYPGKARNATELRRDLELAMSLIPGAKRLNLHAIYLESDVPVGRDKIEPRHFANWVE WAKQQGVGLDFNPSCFSHPLSADGMTLSHPDAAVRQFWIDHCKASRRISAYFGKELGTAS VMNIWIPDGMKDLPADRLGPRQRLLAALDEVLTEKFDEAHHIDAVESKLFGIGAESYTVG SNEFYMGYASSRDIALCLDAGHFHPTEIISDKISAVSLFIRHLLLHVSRPVRWDSDHVVL LDDETQAIANEIVRNELLNRVHIGLDFFDASINRVSAWVIGTRNMKKALLRALLEPIASL RQAEQEGDYATRLGLMEETRSLPWQAVWDYACASENVPVGADWLKVVKQYEQDVLRSRS