Protein Info for HGI48_RS01250 in Dickeya dianthicola 67-19

Annotation: amino acid ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 392 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 51 to 71 (21 residues), see Phobius details amino acids 86 to 111 (26 residues), see Phobius details amino acids 129 to 147 (19 residues), see Phobius details amino acids 177 to 198 (22 residues), see Phobius details amino acids 218 to 238 (21 residues), see Phobius details amino acids 251 to 273 (23 residues), see Phobius details amino acids 333 to 352 (20 residues), see Phobius details amino acids 361 to 383 (23 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 82 to 146 (65 residues), 60.1 bits, see alignment E=1.3e-20 PF00528: BPD_transp_1" amino acids 260 to 386 (127 residues), 59 bits, see alignment E=2.6e-20

Best Hits

Swiss-Prot: 77% identical to YHDX_ECOLI: Putative amino-acid ABC transporter permease protein YhdX (yhdX) from Escherichia coli (strain K12)

KEGG orthology group: K09970, general L-amino acid transport system permease protein (inferred from 96% identity to ddd:Dda3937_01577)

Predicted SEED Role

"Glutamate Aspartate transport system permease protein GltJ (TC 3.A.1.3.4)" (TC 3.A.1.3.4)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9R8T8 at UniProt or InterPro

Protein Sequence (392 amino acids)

>HGI48_RS01250 amino acid ABC transporter permease (Dickeya dianthicola 67-19)
MLQRPTVKGDLSLTNPAVRAWLYQILAVVIVVVTVGYLLHNTVTNLAQRGITSGFAFLNN
SAGFGIVQHLIDYEQGDTYARVFVVGLLNTLLVSVICIVCASLLGFIVGLARLSDNWLLR
KLSTIYIETFRNIPPLLQIFFWYFAVLRNLPGPRQAVNALDTFFLSNRGLYIPAAEFGPG
AFASILALIITLVVAAVIFRRNKSYHAFTGQQRRSWPILLAVLVTLLGLSQLIFGRALHW
DVPVLKGFNFSGGLVLIPELAALALALSVYTSSFIAEIIRSGIQSVSYGQHEAALSLGLP
KPVTLRKVILPQALRVIIPPLTSQYLNVVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAIE
TIAITMSVYLIISLLISLLMNIYNRKIALIER