Protein Info for HGI48_RS00105 in Dickeya dianthicola 67-19

Annotation: oxalyl-CoA decarboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 581 transmembrane" amino acids 435 to 454 (20 residues), see Phobius details TIGR03254: oxalyl-CoA decarboxylase" amino acids 20 to 575 (556 residues), 966.3 bits, see alignment E=2.6e-295 PF02776: TPP_enzyme_N" amino acids 22 to 139 (118 residues), 103.6 bits, see alignment E=9.2e-34 PF00205: TPP_enzyme_M" amino acids 214 to 346 (133 residues), 120.1 bits, see alignment E=8.6e-39 PF02775: TPP_enzyme_C" amino acids 423 to 556 (134 residues), 82.7 bits, see alignment E=3.8e-27

Best Hits

KEGG orthology group: K01577, oxalyl-CoA decarboxylase [EC: 4.1.1.8] (inferred from 94% identity to dda:Dd703_2502)

Predicted SEED Role

"Oxalyl-CoA decarboxylase (EC 4.1.1.8)" in subsystem Alkaloid biosynthesis from L-lysine (EC 4.1.1.8)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9R885 at UniProt or InterPro

Protein Sequence (581 amino acids)

>HGI48_RS00105 oxalyl-CoA decarboxylase (Dickeya dianthicola 67-19)
MSSISEINTEINATSENTALIDGFHLFLNALKLNDIDTLFGLPGIPITDLLRMAQAEGMR
VISFRHEQHAGNAAAAAGFLSAKPGICMTVSAPGFLNGLTALANATTNCFPMILISGSSE
REIVDLQQGDYEEMDQLAIARPLCKAAFRVLRAEDIGVGIARAIRAAVSGRPGGVYLDLP
AKLFSQTMPLDAGRKSLIKVVDPAPRQLPAPDTVARALELLKNARKPLILLGKGAAYARA
DAEIRALVEKTGIPYLPMSMAKGLLPDTHELSAAATRSYVLKEADVVVVIGARLNWLLSH
GKGKTWGPENGPKKFIQIDIAPTEIDSNVAIDAPLIGDVSSCVTALLSGIGNDWAKPSTD
WTGAIAERRAKNINKMADMLAARPSPMNFHSALSVVKAVVKDNPEAIVVSEGANTLDFGR
SIVDMYLPRKRLDVGTWGIMGIGMGFAVAGAVVTGKPVIAIEGDSAFGFSGMEVETLCRY
HLPVCVVVFNNNGIYKGTDTNASGGTDMAPTVFVKDARYEMMMQAFGGVGVHVTTADELH
RAMNEAIACGKPTLINAVIDETVGTESGRITNLNPAKAIKK