Protein Info for HER17_RS21115 in Pectobacterium carotovorum WPP14

Annotation: methyl-accepting chemotaxis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 630 transmembrane" amino acids 15 to 36 (22 residues), see Phobius details amino acids 282 to 302 (21 residues), see Phobius details PF16591: HBM" amino acids 50 to 276 (227 residues), 53.1 bits, see alignment E=4.9e-18 PF00672: HAMP" amino acids 301 to 352 (52 residues), 35.5 bits, see alignment 1.5e-12 PF00015: MCPsignal" amino acids 416 to 571 (156 residues), 189.4 bits, see alignment E=7.4e-60

Best Hits

KEGG orthology group: K05875, methyl-accepting chemotaxis protein II, aspartate sensor receptor (inferred from 94% identity to eca:ECA0091)

Predicted SEED Role

"Methyl-accepting chemotaxis protein II"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (630 amino acids)

>HER17_RS21115 methyl-accepting chemotaxis protein (Pectobacterium carotovorum WPP14)
MAMNFDNLKVGKKLGLGFFLILLMTMVIAGAGIMHIGSLKDSINKVNLSNDINDEINQAK
YYRALYGTTYNPDDIKKNVEHIANVSKLAEKAKEFHWPESDAKKIASIPALITSYQEKQS
NYINAVGKKDAVRKSWNISTTEKPLEQLNDQLKTDNNSANLQLLLSDLNQKLIAVRYHVR
GLLLSTNKESEEKLTDAINAAQTSLTFLYQSLSAEQRETLSPVLAIMNNYEEQVLAYMPA
YEEEMAQAGQMRGVAEQLNSVVKGLLSDQLAASQEDIRNATLQMSIAALITLLLGLLISW
FISRQITTPLGNTLNMAEKIATGDLTMSINTTRKDELGQLMSAMSKMNDNLHNMIDDIRV
GVSQISNASSEIVAGNTDLSSRTEQQAAAVEQTAASMEQLTATVKQNADNAHHANKLAIS
ASQTAKQGGEQVNNVVQTMTAIESSSKRIAEITSVINSIAFQTNILALNAAVEAARAGEQ
GRGFAVVASEVRSLAQRSSQAAKEIEGLISESVTQVSRGATLVGNAGKTMNDIVTSITQV
HDIMGEIATASDEQSRGISQVSQAIVEMDSTTQQNAALVEQSSAAADSLEEQARLLKQAV
SVFRLANAQHDDTPAGIAFADQTHRLHAPR