Protein Info for HER17_RS21105 in Pectobacterium carotovorum WPP14

Annotation: formate dehydrogenase accessory sulfurtransferase FdhD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00129: formate dehydrogenase family accessory protein FdhD
  • amino acids 36 to 276 (241 residues), 300.3 bits, E=4.4e-94
• PF02634: FdhD-NarQ
  • amino acids 40 to 275 (236 residues), 232.8 bits, E=2.5e-73

Best Hits

Swiss-Prot: 95% identical to FDHD_PECAS: Sulfur carrier protein FdhD (fdhD) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K02379, FdhD protein (inferred from 95% identity to pct:PC1_4159)

Predicted SEED Role

"Formate dehydrogenase chain D (EC 1.2.1.2)" in subsystem Formate hydrogenase (EC 1.2.1.2)

MetaCyc Pathways

• formate oxidation to CO₂ (1/1 steps found)
• oxalate degradation VI (1/4 steps found)
• oxalate degradation III (1/5 steps found)
• superpathway of C1 compounds oxidation to CO₂ (4/12 steps found)
• purine nucleobases degradation II (anaerobic) (12/24 steps found)
• purine nucleobases degradation I (anaerobic) (5/15 steps found)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Methane metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.2.1.2

Use Curated BLAST to search for 1.2.1.2

Protein Sequence (277 amino acids)

>HER17_RS21105 formate dehydrogenase accessory sulfurtransferase FdhD (Pectobacterium carotovorum WPP14)
MQVFQVEGVHLPADAALEGATQHSVYHPGSLQQPQSDWLAEEVPVALVYNGISHVVMMAS
PKELEQFALGFSLSEGIIQSPADIYGIDVQAACNGIEVQIELSSRRFAGLKERRRAMDGR
TGCGVCGVEQLAEIGKPIAPLPFTQTFSLSKLENALVRLRDVQKIGQVTGCTHAASWVAP
DGTLSGGSEDVGRHVALDKLLGTRAKQGWQQGAALVSSRASYEMVQKSAMCGVEILFAVS
AATSLAVEVAQRCNLTLVGFCRPGHATIYTHPQRLSA