Protein Info for HER17_RS20420 in Pectobacterium carotovorum WPP14

Annotation: shikimate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 465 transmembrane" amino acids 45 to 70 (26 residues), see Phobius details amino acids 82 to 105 (24 residues), see Phobius details amino acids 117 to 136 (20 residues), see Phobius details amino acids 143 to 169 (27 residues), see Phobius details amino acids 182 to 205 (24 residues), see Phobius details amino acids 217 to 236 (20 residues), see Phobius details amino acids 274 to 298 (25 residues), see Phobius details amino acids 310 to 333 (24 residues), see Phobius details amino acids 341 to 360 (20 residues), see Phobius details amino acids 366 to 385 (20 residues), see Phobius details amino acids 406 to 427 (22 residues), see Phobius details amino acids 433 to 453 (21 residues), see Phobius details PF00083: Sugar_tr" amino acids 50 to 450 (401 residues), 87 bits, see alignment E=1.3e-28 TIGR00883: MFS transporter, metabolite:H+ symporter (MHS) family protein" amino acids 51 to 448 (398 residues), 475.4 bits, see alignment E=7.6e-147 PF07690: MFS_1" amino acids 64 to 325 (262 residues), 64.2 bits, see alignment E=1.1e-21 amino acids 291 to 453 (163 residues), 45.9 bits, see alignment E=3.9e-16

Best Hits

Swiss-Prot: 74% identical to SHIA_ECOLI: Shikimate transporter (shiA) from Escherichia coli (strain K12)

KEGG orthology group: K08172, MFS transporter, MHS family, shikimate and dehydroshikimate transport protein (inferred from 97% identity to eca:ECA0225)

MetaCyc: 74% identical to shikimate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-27

Predicted SEED Role

"Shikimate transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (465 amino acids)

>HER17_RS20420 shikimate transporter (Pectobacterium carotovorum WPP14)
MDTSTTPTLSQPGGSLPQQDDSLSSDKTLQTQSVSHSQHRAKRAAWGSFVGAVVDWYDFL
LYGIVAALVFNTEFFPQVSPTMGTLAAFGTFGVGFLFRPLGGMVFGHFGDKLGRKRMLMI
TVWMMGISTALIGLLPSFDSIGWWAPVLLVTLRAIQGFAVGGEWGGAALLAVENAPKKKK
AFYSSGVQVGFGVGLLLATGSVSVVSNLTTNEEFTTWGWRLPFLFSLILVAIAWWVRNGM
DESQEFEANKTLGERANKLRSFPIMEALRQHPKAFLLIIALRLGELLTMYIVTAFALNYS
TTHLGLSRDIFLNIGLLVGAISCVSIPCFAYLADSFGRRRIYVTGALIGAASAVPFFMAL
ESHNTLLILFFAIMLANIAHDMIVSVQQPMFTELFGTAYRYSGAGVGYQVASVVGGGFTP
FIAVLLVQFMDGSWHAVAAYLAIGCLLSAIVGMRMKATSADALPH