Protein Info for HER17_RS20295 in Pectobacterium carotovorum WPP14

Annotation: amino acid ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 392 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 85 to 111 (27 residues), see Phobius details amino acids 125 to 145 (21 residues), see Phobius details amino acids 180 to 199 (20 residues), see Phobius details amino acids 220 to 240 (21 residues), see Phobius details amino acids 255 to 276 (22 residues), see Phobius details amino acids 334 to 352 (19 residues), see Phobius details amino acids 361 to 383 (23 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 82 to 146 (65 residues), 59.7 bits, see alignment E=1.6e-20 PF00528: BPD_transp_1" amino acids 260 to 387 (128 residues), 62.9 bits, see alignment E=1.7e-21

Best Hits

Swiss-Prot: 77% identical to YHDX_ECOLI: Putative amino-acid ABC transporter permease protein YhdX (yhdX) from Escherichia coli (strain K12)

KEGG orthology group: K09970, general L-amino acid transport system permease protein (inferred from 95% identity to eca:ECA0244)

Predicted SEED Role

"Glutamate Aspartate transport system permease protein GltJ (TC 3.A.1.3.4)" (TC 3.A.1.3.4)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (392 amino acids)

>HER17_RS20295 amino acid ABC transporter permease (Pectobacterium carotovorum WPP14)
MLQRPTVKGDLSLTNPAVRAWLYQIVVVIAVLAVAAYLLHNTVTNLAQRGITSGFDFLNK
SAGFGIVQHLIDYQQGDTYARVFVVGLFNTLLVSALCIVFASILGFTVGLARLSDNWLLR
KISNIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQSISAFDVAFLSNRGFYLPSPELGPG
AAAFFLSLLITAIVTWVVFRRNKRYHALTGQPRRTWPLTLGLFLVLCTLSHLIFGPAFHW
DMPELKGFNFRGGMVLIPELAALTVALSVYTSSFIAEIIRSGIQSVSHGQHEAARSLGLP
NPVTLRKVILPQALRVIIPPLTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAIE
TIAITMSVYLIISLLISLLMNLYNRKIALVER