Protein Info for HER17_RS20290 in Pectobacterium carotovorum WPP14
Annotation: amino acid ABC transporter substrate-binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 85% identical to YHDW_ECO57: Putative amino-acid ABC transporter-binding protein YhdW (yhdW) from Escherichia coli O157:H7
KEGG orthology group: K09969, general L-amino acid transport system substrate-binding protein (inferred from 100% identity to pct:PC1_0229)Predicted SEED Role
"Glutamate Aspartate periplasmic binding protein precursor GltI (TC 3.A.1.3.4)" (TC 3.A.1.3.4)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (341 amino acids)
>HER17_RS20290 amino acid ABC transporter substrate-binding protein (Pectobacterium carotovorum WPP14) MKRIVISTLVAGASLFAAINQAHAGATLDAIQKKGFVQCGISDGLPGFSYADASGKYSGI DVDVCRGLAAAVFGDANKVKYTPLTAKERFTALQSGEVDVLSRNTTWTSSRDGGMGMLFT GVTYYDGIGFLTHNKAGLTSAKELDGATVCIQAGTDTELNVADYFKTHKMQYTPVTFDRS DESAKALESGRCDTLASDQSQLYALRIKLSKPAEFIVLPEVISKEPLGPVVRRGDEEWFA IVRWTLFAMLNAEEMGVTSKNVDQLAAKPTTPDMSHLLGHEGSYGKDLKLPNDWAFKIIK QVGNYGEIFERNVGMGSELKIKRGLNELWNKGGIQYAPAVR