Protein Info for HER17_RS19655 in Pectobacterium carotovorum WPP14

Annotation: sucrose-6-phosphate hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01322: sucrose-6-phosphate hydrolase
  • amino acids 18 to 442 (425 residues), 530.3 bits, E=1.9e-163
• PF00251: Glyco_hydro_32N
  • amino acids 31 to 336 (306 residues), 353.7 bits, E=1.1e-109
• PF08244: Glyco_hydro_32C
  • amino acids 361 to 447 (87 residues), 41 bits, E=2e-14

Best Hits

KEGG orthology group: K01193, beta-fructofuranosidase [EC: 3.2.1.26] (inferred from 96% identity to pct:PC1_0348)

Predicted SEED Role

"Sucrose-6-phosphate hydrolase (EC 3.2.1.B3)" (EC 3.2.1.B3)

MetaCyc Pathways

• sucrose degradation III (sucrose invertase) (4/4 steps found)
• sucrose degradation V (sucrose α-glucosidase) (3/5 steps found)
• inulin degradation (1/3 steps found)

KEGG Metabolic Maps

• Galactose metabolism
• Starch and sucrose metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.26 or 3.2.1.B3

Protein Sequence (469 amino acids)

>HER17_RS19655 sucrose-6-phosphate hydrolase (Pectobacterium carotovorum WPP14)
MKEVHLLKRMAHALMSGHSRKQEDPYRPEWHLSPSVGLLNDPNGFIHHNGRYHLFYQWNP
LSCAHGAKFWGHWSSVDLVNWMHEPVALVPSESYESHGCYSGSAVADQGAIMLVYTGNVK
YDDGSRTAFQCLARENPNGEYDKLGAVLTLPDGYTGHVRDPKVWRQDDHWYMVLGAQDLD
LQGKVLLYRSADLLAWEKIGEIAGSRLGGLGDFGYMWECPDLFPLDGKDVLICCPQGVPA
EEERYLNTFQAGYFIGSLNYENGTYPHQDFHELDLGFEFYAPQTTLSEDGRRLLFGWMSI
PDDNEFFEPTIEQGWIHTMTCPRELTLHGDRVYQRPARELQQLRRQHYTWHGAADYASPL
HASSAEILITVQGEFQFNLASQLVLCWDGERVTLSRRNRRTGEPEHRYWRGDLSQLQILC
DRSSVEIFINDGEAVMSARYFPESEATMTFSGSGRLTLQHWLLAPCVIE