Protein Info for HER17_RS19040 in Pectobacterium carotovorum WPP14

Annotation: NupC/NupG family nucleoside CNT transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 transmembrane" amino acids 6 to 22 (17 residues), see Phobius details amino acids 31 to 51 (21 residues), see Phobius details amino acids 63 to 82 (20 residues), see Phobius details amino acids 94 to 118 (25 residues), see Phobius details amino acids 173 to 194 (22 residues), see Phobius details amino acids 199 to 221 (23 residues), see Phobius details amino acids 261 to 288 (28 residues), see Phobius details amino acids 294 to 315 (22 residues), see Phobius details amino acids 364 to 388 (25 residues), see Phobius details amino acids 401 to 424 (24 residues), see Phobius details TIGR00804: nucleoside transporter, NupC family" amino acids 5 to 422 (418 residues), 504.7 bits, see alignment E=9.8e-156 PF01773: Nucleos_tra2_N" amino acids 8 to 81 (74 residues), 86.1 bits, see alignment E=2.8e-28 PF07670: Gate" amino acids 98 to 196 (99 residues), 72.5 bits, see alignment E=5.5e-24 PF07662: Nucleos_tra2_C" amino acids 201 to 420 (220 residues), 279.3 bits, see alignment E=3.3e-87

Best Hits

Swiss-Prot: 50% identical to PSUT_ECOLI: Putative pseudouridine transporter (psuT) from Escherichia coli (strain K12)

KEGG orthology group: K03317, concentrative nucleoside transporter, CNT family (inferred from 98% identity to eca:ECA0473)

Predicted SEED Role

"Nucleoside permease NupC" in subsystem Deoxyribose and Deoxynucleoside Catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (425 amino acids)

>HER17_RS19040 NupC/NupG family nucleoside CNT transporter (Pectobacterium carotovorum WPP14)
MQLVMSLIGMIVLILCAVMLSNNRKAIRLRTVAGAFILQIGIGALVLYVPVGRKILEGLT
GGVANVIAYGNQGVSFMFGGLVSDKMFEVFGGGGFVFALRVLPIIVFFSSLIAVLYYMGI
MQIVIKVLGGGLQKLLGTSRTESLSATANIFVGQTEAPLVVRPYIANMTQSELFAVMCGG
LASIAGAVMAGYAQMGVPLEYLIAASFMAAPGGLLFAKLMVPETEKTHDHDEMVGFVDED
DRPANVIDAAASGAASGMQLALNVGAMLLAFIALIAVLNGILGGIGGWFDYPQLSLELIL
GWCFAPVAFLIGIPWSEATVAGSFIGQKLIVNEFVAYLNFSEYLKADEVVQAAGLQVLSD
HTKAVISFALCGFANLSSIAILIGGLGSMAPTRRQDIARFGLKAVAAGTLSNLMSACIAG
FFLAL