Protein Info for HER17_RS18250 in Pectobacterium carotovorum WPP14

Annotation: amino acid adenylation domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1032 transmembrane" amino acids 60 to 81 (22 residues), see Phobius details PF00501: AMP-binding" amino acids 15 to 359 (345 residues), 231.9 bits, see alignment E=2.3e-72 TIGR01733: amino acid adenylation domain" amino acids 34 to 434 (401 residues), 331 bits, see alignment E=5e-103 PF13193: AMP-binding_C" amino acids 418 to 491 (74 residues), 27.9 bits, see alignment 7.4e-10 PF00550: PP-binding" amino acids 520 to 579 (60 residues), 38.7 bits, see alignment 1.9e-13 PF00668: Condensation" amino acids 608 to 1022 (415 residues), 158.8 bits, see alignment E=3.9e-50

Best Hits

KEGG orthology group: None (inferred from 92% identity to pct:PC1_0578)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1032 amino acids)

>HER17_RS18250 amino acid adenylation domain-containing protein (Pectobacterium carotovorum WPP14)
MMKNRKTVFEIISEWSLKSPEKTAVEFNGDRLNYQQLESQSRHLADYLLSHYPDNKRGRI
AVYLEPGVMMPVVLLAILKAGHTYVPLSHFHPSERIMQILDDSSTFLLISTRAMLNKTAI
DKVFPSTIVLEDIHYSAELVATLPPVCENDLAYILYTSGSTGKPKGVAIEHRNLSYYLNW
FNEDVWPETRATLPLTSTLSFAAAVTQLYAPLLRGDTLFILPADSLNEPEVLLRWHQQHP
DGATYCVPTVWDELLRYQASSSHAWALPKTVFLSGEPVSFDLKERTFQQIPDVRLFNLYG
PTETTANCSFAELKSGKSVTLGKALRGSEIMIVDENLRPVAEGEEGEICAFGEGVARGYI
NRDELTQQRFFTHVRADKRSWGHRTGDLGKMTPEGEILYLGRIDRQIKINGIRIEPEEVE
IVLRQHGDIDKALVRPIQENGRQRLVAYLVSRNPSLATNDLRRFLQDKLPRAMHPSHFIM
LETLPKLPNGKLDVSRLPEPCPQRPELGYPVKAAGNELEQELIDIWQEVLGFRELGANDN
FFDLGGDSLQAMKARLLIRKRLFSEIDYPLFFNNATPHLLAFIVPYYVNDDEPTSDENNA
DIEALAPSSQQRYFLTLDQLSSEPSAYQLAFRLTIKGPLDESAVELSIRRILEGNPVLRT
RFDLDRLQCLEGDYPIEAIPIERLTAFSPDGGKNTLSDRRLLELISIPEMDVEHSPLICF
HLISLTTQRHILLGRVHHTVFDHDAIGLFFHQFVDYVRAYSAGDRSYRIGSEERYLRYRQ
QQRRTKDQCHPRERQFWLDKMEDYLAAGADATAFPLSDCQDGENYWCILSDTLTQAIKHY
AQQHRTTPFVCMLTAFTQLLKTTNYRHVPIGIPVSNRMLTENATTIGCFVNMVAYYDDSP
AQESFSTLLARSQNKIHAILDHQTLPYDVLMADVRAKGWSDKLRFPVSFNYLTAMPPAVQ
INETAYQITDIANHQARLDLTLSVYDDEALALCFNYQQAAFNAEEIAALSHQYHQILMDV
VQPNTALLCSNL