Protein Info for HER17_RS17130 in Pectobacterium carotovorum WPP14

Annotation: anaerobic nitric oxide reductase flavorubredoxin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 509 PF00753: Lactamase_B" amino acids 34 to 172 (139 residues), 48.5 bits, see alignment E=2.7e-16 PF19583: ODP" amino acids 35 to 228 (194 residues), 64 bits, see alignment E=4.7e-21 PF12706: Lactamase_B_2" amino acids 45 to 149 (105 residues), 29 bits, see alignment E=2e-10 PF00258: Flavodoxin_1" amino acids 256 to 389 (134 residues), 63.5 bits, see alignment E=6.1e-21 PF00301: Rubredoxin" amino acids 460 to 505 (46 residues), 68.7 bits, see alignment 9.1e-23

Best Hits

Swiss-Prot: 97% identical to NORV_PECAS: Anaerobic nitric oxide reductase flavorubredoxin (norV) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K12264, anaerobic nitric oxide reductase flavorubredoxin (inferred from 97% identity to eca:ECA0902)

MetaCyc: 81% identical to anaerobic nitric oxide reductase flavorubredoxin (Escherichia coli K-12 substr. MG1655)
1.18.98.-

Predicted SEED Role

"Anaerobic nitric oxide reductase flavorubredoxin" in subsystem Nitrosative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (509 amino acids)

>HER17_RS17130 anaerobic nitric oxide reductase flavorubredoxin (Pectobacterium carotovorum WPP14)
MTIHVKNNIHWVGQRDWEVRDFHGTEYKTLQGSSYNSYLIREEKTVLIDTVDHKFSREFV
QNLMAEVDLNTIDYIVINHAEEDHAGALSELMARIPNTPIYCTHNAIDSITGHHHHPEWN
FHTVKTGDTLDIGNGKQLIFIETPMLHWPDSMMTYMTEDAVLFSNDAFGQHYCDEHLFND
EVDQTELFEQCQRYFANILTPFSRLVTAKIHEVLGFNLPLSMVATSHGVVWRDDPAQIIH
LYLKWADSYQEDRITLFYDTMSNNTRMMADAIAQGINDVDPGVAVKIYNVARHDKNEILT
QVFRSKGVLVGSSTMNNVMMPKVAAMLEEITGLRFQNKKASAFGSYGWNGGAVDRVQTRL
MDAGFETTLALKTKWRPDGSALEICRNHGREIARQWALHPLDDTPARRVISPVKQTAAAP
QTTTAPQNVSAPAESACGCNEVAAPQSTAQPAVQSENGCMVCSVCQWIYDPALGEPMQDV
TPGTMWSDVPDSFLCPECGLGKDVFNPIR