Protein Info for HER17_RS17065 in Pectobacterium carotovorum WPP14

Annotation: 4Fe-4S dicluster domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 232 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF12838: Fer4_7" amino acids 51 to 116 (66 residues), 31.3 bits, see alignment E=7.9e-11 PF13247: Fer4_11" amino acids 94 to 189 (96 residues), 88.2 bits, see alignment E=1.2e-28 PF00037: Fer4" amino acids 127 to 147 (21 residues), 22.8 bits, see alignment (E = 2.2e-08)

Best Hits

KEGG orthology group: K04014, formate-dependent nitrite reductase, Fe-S protein (inferred from 97% identity to pwa:Pecwa_1033)

Predicted SEED Role

"NrfC protein" in subsystem Nitrate and nitrite ammonification

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (232 amino acids)

>HER17_RS17065 4Fe-4S dicluster domain-containing protein (Pectobacterium carotovorum WPP14)
MEELSRRRFIAYMGSAIAVSGNIGLAQAQNEPEKTPGKVAIKYGLLHNEMRCIGCKACIK
ACKETNSVPDGVTRLDILQTVDIPAVEKTRAIKQFFRKSCQHCENPPCVAVCPTGASFKD
ALTGIVDVNDKRCVGCRYCIAACPYHVRFINPVTKTADKCNFCRETNLAAGKQPACVEIC
PTKALVFGDLNDPESNIAKMIESNATYRSKVYLGTEPQLYRIPGKRGAIDNA