Protein Info for HER17_RS16070 in Pectobacterium carotovorum WPP14

Annotation: GntR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 248 PF00392: GntR" amino acids 25 to 87 (63 residues), 60 bits, see alignment E=2.1e-20 PF08220: HTH_DeoR" amino acids 52 to 82 (31 residues), 22.3 bits, see alignment 1.3e-08 PF07702: UTRA" amino acids 108 to 242 (135 residues), 122.4 bits, see alignment E=1.9e-39

Best Hits

Swiss-Prot: 83% identical to YEGW_ECOLI: Uncharacterized HTH-type transcriptional regulator YegW (yegW) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 97% identity to pwa:Pecwa_3308)

Predicted SEED Role

"Uncharacterized HTH-type transcriptional regulator YegW"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (248 amino acids)

>HER17_RS16070 GntR family transcriptional regulator (Pectobacterium carotovorum WPP14)
MEHAHTRLIEQLTQRFAATDNTPLYLKFAETVKNAVRSGTLEHGNILPGERDLSQLAGVS
RITVRKAMQTLEEEGVVTRVRGYGTQINNIFEYSLKEARGFSQQVVLRGKKPNTLWVNKQ
IVKSSKEVAEQLAIAPDTPVFLLKRIRYVDEDAVSIEESYVPVDLIADADDIGVSLYDYF
RSQNINPQRTRSRVSARMPDAEFQSHIQLDNKVPVLVIKQIALDPQNRPIEYSISYCRSD
LYVFVCEE