Protein Info for HER17_RS15715 in Pectobacterium carotovorum WPP14

Annotation: DUF454 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 131 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details transmembrane" amino acids 73 to 92 (20 residues), see Phobius details amino acids 99 to 117 (19 residues), see Phobius details PF04304: DUF454" amino acids 3 to 116 (114 residues), 140.4 bits, see alignment E=1.3e-45

Best Hits

Swiss-Prot: 71% identical to YBAN_SHIFL: Inner membrane protein YbaN (ybaN) from Shigella flexneri

KEGG orthology group: K09790, hypothetical protein (inferred from 95% identity to eca:ECA1174)

Predicted SEED Role

"Hypothetical protein DUF454" in subsystem Heme, hemin uptake and utilization systems in GramPositives

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (131 amino acids)

>HER17_RS15715 DUF454 family protein (Pectobacterium carotovorum WPP14)
MYRVLLMILGWVSVVLATLGVVLPLLPTTPFLLLAAWCFARSSPRFHDWLLYRSWFGSYL
RHWQQHRALPPGAKWKAVTMILLTFALSLWLVKLVWVRILLLVILAILLTFMLRLPVIDP
EQQTQGADPKR