Protein Info for HER17_RS14480 in Pectobacterium carotovorum WPP14

Annotation: chorismate mutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01817: CM_2
  • amino acids 32 to 100 (69 residues), 51.1 bits, E=7.3e-18
• TIGR01806: putative chorismate mutase
  • amino acids 32 to 137 (106 residues), 102.8 bits, E=6e-34

Best Hits

KEGG orthology group: K01850, chorismate mutase [EC: 5.4.99.5] (inferred from 94% identity to eca:ECA1449)

Predicted SEED Role

"Periplasmic chorismate mutase I precursor (EC 5.4.99.5)" in subsystem Chorismate Synthesis or Phenylalanine and Tyrosine Branches from Chorismate (EC 5.4.99.5)

MetaCyc Pathways

• superpathway of chorismate metabolism (53/59 steps found)
• superpathway of aromatic amino acid biosynthesis (18/18 steps found)
• superpathway of L-phenylalanine biosynthesis (10/10 steps found)
• superpathway of L-tyrosine biosynthesis (10/10 steps found)
• L-phenylalanine biosynthesis I (3/3 steps found)
• L-tyrosine biosynthesis I (3/3 steps found)
• L-tyrosine biosynthesis III (3/4 steps found)
• L-phenylalanine biosynthesis II (2/4 steps found)
• L-tyrosine biosynthesis II (2/4 steps found)
• superpathway of L-phenylalanine and L-tyrosine biosynthesis (2/5 steps found)
• bacilysin biosynthesis (1/10 steps found)
• salinosporamide A biosynthesis (3/15 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from shikimate pathway
• Biosynthesis of phenylpropanoids
• Phenylalanine, tyrosine and tryptophan biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 5.4.99.5

Use Curated BLAST to search for 5.4.99.5

Protein Sequence (185 amino acids)

>HER17_RS14480 chorismate mutase (Pectobacterium carotovorum WPP14)
MNLPISAVISLMMSSVWCVPLYAATQDNPLGIYQLIQERMVLMKDVAGYKARQHLPVEDL
KQEDRILSKVREQSAAVGLSPQSTQLFFTSLMNASKAIQYRYMADWLATPESDWTPLSLN
DTIRPTLLTIDDQLLVSIKRYLANGGHFAPQQEATFLSSINVEHLSQNDKRQIYAALSQI
EPDGK