Protein Info for HER17_RS13915 in Pectobacterium carotovorum WPP14

Annotation: LuxR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 245 PF03472: Autoind_bind" amino acids 14 to 157 (144 residues), 121.1 bits, see alignment E=2.9e-39 PF00196: GerE" amino acids 179 to 233 (55 residues), 51.4 bits, see alignment E=6.4e-18

Best Hits

Swiss-Prot: 73% identical to ECHR_DICCH: Transcriptional activator protein EchR (echR) from Dickeya chrysanthemi

KEGG orthology group: K07782, LuxR family transcriptional regulator (inferred from 98% identity to eca:ECA1561)

Predicted SEED Role

"N-3-oxohexanoyl-L-homoserine lactone quorum-sensing transcriptional activator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (245 amino acids)

>HER17_RS13915 LuxR family transcriptional regulator (Pectobacterium carotovorum WPP14)
MSVFCSDNEIINNTIKSYLGRKLKQYGDLKYAYMIMNKKNPSQVVIISNYPQEWVNTYKE
NNYQHIDPVILTAINKVSPFSWEDNIVINSKLKFSKIFNLSKEYDIVNGYTFVLHDNNNN
LAALSIMFEEHAPTDMENIVEENKDKLQMLLIAVHEKITTLYKEMTQSPQSRKQGDKEIF
SQRENEILYWASMGKTYPEIALILDIKISTVKFHIGNVVKKLGVLNAKHAIRLGVELQLI
KPEPL