Protein Info for HER17_RS13900 in Pectobacterium carotovorum WPP14

Annotation: MlaD family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 547 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details PF02470: MlaD" amino acids 44 to 134 (91 residues), 53.4 bits, see alignment E=1.2e-18 amino acids 159 to 219 (61 residues), 46 bits, see alignment E=2.6e-16 amino acids 290 to 394 (105 residues), 41.4 bits, see alignment E=6.9e-15

Best Hits

KEGG orthology group: K06192, paraquat-inducible protein B (inferred from 92% identity to pct:PC1_1445)

Predicted SEED Role

"Paraquat-inducible protein B" in subsystem Oxidative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (547 amino acids)

>HER17_RS13900 MlaD family protein (Pectobacterium carotovorum WPP14)
MIHEQPGDPVIIRQRWRISLIWLVPALAMLMGLAMLIHTWSDTGPEIVISFQSASGLEAG
RTVVKYKDVAVGSVKDISLSQDSQQVLVTIQLNKNAENLAHADSRFWVVRPRVAINGVTG
IDTLLSGAYIGADKGESTQEETRFVGLESPPAVINGMPGSRFVIQADDLGSLDSGSPVYY
RRIPVGRVASYQLNRDGHSVQLQVFIDAPYDRFVTPNTRFWNASGVDLSVDANGFRLRTQ
TLAAVMAGGIAFSTPDLDDTIARPEPLTTYKLASDRESALSPPDGPPILFKLRFDRSLHG
LEIGAPVEFSSVKIGYVTAIALDYSKTGYRFPTVVSIEVFPNRLGDVLDRLPKQATSLEQ
QTAEFTRDLVEHGLRAQVAPSNLLTGQLYISLDFVPEAAKTPFDLNARPLVLPTVDGGFD
RLQTQMASIIGKIDNLPLDAIGRNMNTTLVEANKALRQVNGQTLPEANRLMKQMQQATRR
AQDVLEEDSPLQLGITQSLQEIQRTLRALRSLAEQIDRHPESLLQGRPSDSSSAVNRDPL
SREGSSR