Protein Info for HER17_RS12490 in Pectobacterium carotovorum WPP14

Annotation: putrescine ABC transporter permease PotH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 transmembrane" amino acids 35 to 58 (24 residues), see Phobius details amino acids 106 to 127 (22 residues), see Phobius details amino acids 138 to 159 (22 residues), see Phobius details amino acids 189 to 211 (23 residues), see Phobius details amino acids 232 to 256 (25 residues), see Phobius details amino acids 288 to 309 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 121 to 307 (187 residues), 74.7 bits, see alignment E=4e-25

Best Hits

Swiss-Prot: 83% identical to POTH_ECOLI: Putrescine transport system permease protein PotH (potH) from Escherichia coli (strain K12)

KEGG orthology group: K11075, putrescine transport system permease protein (inferred from 96% identity to eca:ECA2675)

MetaCyc: 83% identical to putrescine ABC transporter membrane subunit PotH (Escherichia coli K-12 substr. MG1655)
ABC-25-RXN [EC: 7.6.2.11, 7.6.2.16]

Predicted SEED Role

"Putrescine transport system permease protein PotH (TC 3.A.1.11.2)" in subsystem Polyamine Metabolism (TC 3.A.1.11.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.11 or 7.6.2.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (321 amino acids)

>HER17_RS12490 putrescine ABC transporter permease PotH (Pectobacterium carotovorum WPP14)
MTSFPEHNTAEPPGKARLWLRVLMARWRQKHGRKLVIALPYLWLLLLFMLPFLIVFKISL
AEMARAIPPYTDLVSWLDGKLDISLNLGNYLHLLDDPLYFDAYMQSLQVAAVSTLCCLLI
GYPLAWAVAHSKPSTRNILLLLVILPSWTSFLIRVYAWMGILKNNGILNNFLLWLGVIDE
PLVILHTNLAVYIGVVYSYLPFMVLPIYTALMRLDYSLVEASLDLGARPLRTFFNVIVPL
TKGGIIAGSMLVFIPAVGEYVIPELLGGPDSIMIGRILWQEFFNNRDWPVASAVAVVMLL
LLIMPIIWFHKHQSKTAEGEA