Protein Info for HER17_RS12355 in Pectobacterium carotovorum WPP14

Annotation: DNA translocase FtsK 4TM domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1164 transmembrane" amino acids 22 to 44 (23 residues), see Phobius details amino acids 75 to 98 (24 residues), see Phobius details amino acids 110 to 131 (22 residues), see Phobius details amino acids 137 to 155 (19 residues), see Phobius details amino acids 163 to 184 (22 residues), see Phobius details PF13491: FtsK_4TM" amino acids 20 to 191 (172 residues), 159.8 bits, see alignment E=1e-50 PF17854: FtsK_alpha" amino acids 674 to 774 (101 residues), 101.9 bits, see alignment E=3.9e-33 PF01580: FtsK_SpoIIIE" amino acids 782 to 995 (214 residues), 282.9 bits, see alignment E=3.3e-88 PF09397: FtsK_gamma" amino acids 1099 to 1159 (61 residues), 94.7 bits, see alignment 4.4e-31

Best Hits

Predicted SEED Role

"Cell division protein FtsK" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Bacterial RNA-metabolizing Zn-dependent hydrolases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1164 amino acids)

>HER17_RS12355 DNA translocase FtsK 4TM domain-containing protein (Pectobacterium carotovorum WPP14)
MSQEYTEDKDVTLKKLSGTRRLLEAILIVVALFAVYLSVALLSFSPSDPSWSQTAWHEPI
HNLGGVAGAWLADTLFFIFGVLAYAIPPIMLSLCWAAFRQRDNQQSIEYFTFSLRLIGTL
ALILTSCGLAALNIDDLYYFASGGVLGSLLSSSMIPRFNSMGATLILLCVWGAGLTLFTG
WSWLTIAEKIGAGVLGCLTFMSNRSRHDEDYREEHDREEDERDVLNLRHDEASGEVGTQQ
RDDDDVLFSAPSVADAVNDTASCTEIVESSPLAENAPTATQPAISAETPVTASTLPDVAT
PDSTLSGAAFSGSSSGSGSSSGVVPPVTPSAIDSTPSLNPPLYSFEIPETPAIATSPELH
SSAYVPYGNSYGESAVPPIVTAPVVQPFAEPPQLARDTDSNANNTFMPAFSADGDDNPQI
KRGVGPELPRPNPVRIPTRRELASYGIKLPSQRLAEEQARLQAQSGSAETELANDVYQEE
TPDDIAQQEAALQQAYLDQQRQRYGDEYPLQEDDEDALLQAQLARDFAAQQQSRYDDRAL
QRDEEIPAPIASPVVSAPVQPNPVTSHNAFSFSPFSAESEREPEPHTFSESTYSQPSYRA
EPEFPPMHVGEDGDDDDERNPLTFSQPAQPTSAPVEPVKQETVATPTHHPAMDGLIHPFL
MRNEQPLQKPTTPLPTLDLLTPPPASEAPVDNFALEQTARLIEARLADFRVKADVVDHSP
GPVITRFELDLAPGVKAARISNLSRDLARSLSVVAVRIVEVIPGRPYVGLELPNAHRQTV
YLREVLDCDQFRDNPSPLSIVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMII
SMLYKATPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVGEMERRYKL
MSALGVRNLAGYNERVMTANAMGRPIPDPFWKPGDSMDMTPPVLEKLPYIVVMVDEFADL
MMAVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDS
RTILDQGGAESLLGMGDMLYMAPNSSIPVRVHGAFVRDEEVHAVVQDWKARGRPQYIDNI
VSGGDDAEGGSLGLDGDEELDPLFDQAVEFVVDKRRASISGVQRQFRIGYNRAARIVEQM
EAQGIVSSPGHNGNREVLAPPSME