Protein Info for HER17_RS11980 in Pectobacterium carotovorum WPP14

Annotation: membrane integrity-associated transporter subunit PqiA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 414 transmembrane" amino acids 42 to 62 (21 residues), see Phobius details amino acids 89 to 114 (26 residues), see Phobius details amino acids 134 to 153 (20 residues), see Phobius details amino acids 159 to 178 (20 residues), see Phobius details amino acids 243 to 264 (22 residues), see Phobius details amino acids 283 to 305 (23 residues), see Phobius details amino acids 342 to 363 (22 residues), see Phobius details amino acids 369 to 392 (24 residues), see Phobius details TIGR00155: integral membrane protein, PqiA family" amino acids 2 to 400 (399 residues), 508.4 bits, see alignment E=7.6e-157 PF04403: PqiA" amino acids 40 to 190 (151 residues), 132.5 bits, see alignment E=6e-43 amino acids 243 to 400 (158 residues), 177.8 bits, see alignment E=6.9e-57

Best Hits

Swiss-Prot: 66% identical to PQIA_ECOLI: Intermembrane transport protein PqiA (pqiA) from Escherichia coli (strain K12)

KEGG orthology group: K03808, paraquat-inducible protein A (inferred from 96% identity to pct:PC1_1793)

Predicted SEED Role

"Paraquat-inducible protein A" in subsystem Oxidative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (414 amino acids)

>HER17_RS11980 membrane integrity-associated transporter subunit PqiA (Pectobacterium carotovorum WPP14)
MLCPQCDLLVELPELLHGQKATCPRCKTALTSRQTEPRKRPVGYAVSALFMLLLANLFPF
VSMRVAGITSEITLIQIPKVMVAENYASVATLFMLFVQLVPAFSMATLILLCLHASLPLA
LKKSLGKMLFHLKSWGMAEIFLAGVLVSFVKLMAYGDIGIGTSFMPFVLFCLLQLLAFQS
LDRRWLWNDIVPPPVLPAPPILGQSGLSQGLRSCPCCTAILPANQLICPRCHSRGHARKK
HSLQWTLALLITSIMLYIPSNLMPIMVTEAFGDRMGSTIMSGVVLLWGMGSYPVALVIFV
ASVMVPSLKMLALGWLCWQANGKTKKTEDSERMHVIYEMVEFVGRWSMIDVFVIAVLSAM
VRIGRLMSIYPAIGAVLFAAVVILTMFAAMMFDPRLLWDRRDDVLHKEPAVGER