Protein Info for HER17_RS11345 in Pectobacterium carotovorum WPP14

Annotation: manganese efflux pump MntP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 190 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 21 to 23 (3 residues), see Phobius details amino acids 40 to 62 (23 residues), see Phobius details amino acids 68 to 86 (19 residues), see Phobius details amino acids 106 to 128 (23 residues), see Phobius details amino acids 134 to 155 (22 residues), see Phobius details amino acids 166 to 185 (20 residues), see Phobius details PF02659: Mntp" amino acids 31 to 182 (152 residues), 184.7 bits, see alignment E=4.8e-59

Best Hits

Swiss-Prot: 97% identical to MNTP_PECCP: Putative manganese efflux pump MntP (mntP) from Pectobacterium carotovorum subsp. carotovorum (strain PC1)

KEGG orthology group: None (inferred from 97% identity to pct:PC1_1922)

MetaCyc: 67% identical to Mn2+ exporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-487

Predicted SEED Role

"Putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (190 amino acids)

>HER17_RS11345 manganese efflux pump MntP (Pectobacterium carotovorum WPP14)
MNMSATLILAFGMSMDAFAASIGKGAVLHNPRFRDAIRTGLIFGVIEAITPLIGWALGFF
ASQYILEWDHWVAFTLLLILGGRMIVEGLKGSSDCRCEKVKNHSLALLICTAVATSLDAM
AIGVGLAFLQVNIFHTAMVIGCATMIMVTLGMMIGRYIGPILGKKAEVMGGLVLIGIGCN
ILYEHLGYAA