Protein Info for HER17_RS11185 in Pectobacterium carotovorum WPP14

Annotation: PTS sugar transporter subunit IIC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 445 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 42 to 66 (25 residues), see Phobius details amino acids 95 to 113 (19 residues), see Phobius details amino acids 120 to 140 (21 residues), see Phobius details amino acids 146 to 168 (23 residues), see Phobius details amino acids 224 to 247 (24 residues), see Phobius details amino acids 260 to 282 (23 residues), see Phobius details amino acids 309 to 338 (30 residues), see Phobius details amino acids 340 to 362 (23 residues), see Phobius details amino acids 371 to 396 (26 residues), see Phobius details amino acids 422 to 439 (18 residues), see Phobius details PF03611: EIIC-GAT" amino acids 12 to 406 (395 residues), 394.8 bits, see alignment E=2.3e-122

Best Hits

KEGG orthology group: K03475, PTS system, ascorbate-specific IIC component (inferred from 99% identity to pct:PC1_1954)

Predicted SEED Role

"FIG00732228: membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (445 amino acids)

>HER17_RS11185 PTS sugar transporter subunit IIC (Pectobacterium carotovorum WPP14)
MNTVINFIVKDLLGQASILIALIAMIGLILQKKSVGKTAEGTFKTLLGFLIMMAGINIIV
DTLTYLNSIFTQGFGMKGYITDVAAIAGLANRELGSEVALTLMVIFAVNILIARITPFKY
IFLTGQALLWMATIGTVIGYKSGLTGATLILTGGIFGGIMAVLMPALAQPIVRKITNSDD
VALGHFCTIGYLVQAAVARVVGKNSKSTEDLTLPDNFKFLQDTYLSMAVVMVPMYLIPAV
AAGPAYIAQYANGVNYLMYSFMQSMQFVAGVFVLYSGVRLLLNELVPAFRGIAMRLVPNA
KPALDCPVLFPYAPNAVIVGFLATTVGSILGMLIFPMFGLAMILPGLLTNFFAGGTAGIF
GNALGGRRGAVIGGVVHGLFITLLPAILVPLLEVFGFTGVTFSDSDVISTGLILGHAFQQ
DWLFVAAFVAFVAFIAFIANRKLSQ