Protein Info for HER17_RS10325 in Pectobacterium carotovorum WPP14
Annotation: M20 peptidase aminoacylase family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 49% identical to YXEP_BACSU: Uncharacterized hydrolase YxeP (yxeP) from Bacillus subtilis (strain 168)
KEGG orthology group: None (inferred from 96% identity to pwa:Pecwa_2487)MetaCyc: 49% identical to N-acetyl-sulfur-metabolite deacetylase (Bacillus subtilis subtilis 168)
3.5.1.-
Predicted SEED Role
"N-acetyl-L,L-diaminopimelate deacetylase homolog (EC 3.5.1.18)" (EC 3.5.1.18)
MetaCyc Pathways
- aspartate superpathway (24/25 steps found)
- superpathway of L-lysine, L-threonine and L-methionine biosynthesis I (18/18 steps found)
- L-lysine biosynthesis I (9/9 steps found)
- S-(2-succinyl)-L-cysteine degradation (3/4 steps found)
- S-benzyl-L-cysteine degradation (3/5 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 3.5.1.18
Use Curated BLAST to search for 3.5.1.18
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (398 amino acids)
>HER17_RS10325 M20 peptidase aminoacylase family protein (Pectobacterium carotovorum WPP14) MAESIPCCDTSFEQQLINWRRHLHQYPELSNQEHQTTAHITRWLQEKDIRLLPLALNTGT VAEIGHGSGPTIALRADIDALPIEELVDVPFRSQHAGVMHACGHDFHTAVMLGAACLLKK RESVLPGKVRLFFQPAEEVSTGAKQLIRAGALADVAAVFGLHNAPELPAGTFATRSGPFY ANVDRFAIHITGKGAHAAKPEQGIDSIVTACNIVNALQTLPSRSFSSLESLVISVTRIQG GNTWNVLPQTVELEGTVRTYNAAIRAEIPERIEQLIGGIALALGAKAELKWYPGPPAVVN TSEWADFSKQIARDAGYQVENAELQMSGEDFALYLQDVPGTFVSIGSNSEFGLHHPQFNP DENAIAPASRYFAQLAEAALHRLSTTKATSPQAVLSSS