Protein Info for HER17_RS10240 in Pectobacterium carotovorum WPP14

Annotation: urea ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 422 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF13458: Peripla_BP_6" amino acids 30 to 387 (358 residues), 257.7 bits, see alignment E=3.8e-80 TIGR03407: urea ABC transporter, urea binding protein" amino acids 31 to 404 (374 residues), 595.8 bits, see alignment E=1.3e-183 PF13433: Peripla_BP_5" amino acids 31 to 407 (377 residues), 561.6 bits, see alignment E=1.1e-172

Best Hits

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 99% identity to pct:PC1_2161)

Predicted SEED Role

"Urea ABC transporter, urea binding protein" in subsystem Urea decomposition

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (422 amino acids)

>HER17_RS10240 urea ABC transporter substrate-binding protein (Pectobacterium carotovorum WPP14)
MKRRSLLKVFALSATVVGMGLSWSVQAAETIKVGIMHSLSGTMAISETPLKDVALMTIDE
INAKGGVLGKKLEPVVVDPASNWPLFAEKARQLLTQDKAAVVFGCWTSVSRKSVLPVFEE
LNGLLFYPVQYEGEEMSPNVFYTGAAPNQQAIPAVEYLISEDGGAAKRFFLLGTDYVYPR
TTNKILRAFLHSKGVQDKDIEEVYTPFGHSDYQTIVSNIKKFSTGGKTAVVSTINGDSNV
PFYKELANQGIKATDVPVVAFSVGEEELRGIDTKPLVGHLAAWNYFESVDNPTNADFVEA
YKAYAKAKNLPNAGTVVTNDPMEATYVGIHMWAQAVEKAGTTDVDKVRAAMAGQTFAAPD
GFTLTMDKTNHHLHKPVMIGEIEENGQFNVVWQTDKPVRAQPWSPYIAGNDKKPDHPIKA
AQ