Protein Info for HER17_RS10220 in Pectobacterium carotovorum WPP14

Annotation: glycoside hydrolase family 43 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 558 PF04616: Glyco_hydro_43" amino acids 2 to 236 (235 residues), 227.4 bits, see alignment E=2.5e-71 amino acids 267 to 323 (57 residues), 47.1 bits, see alignment 2.2e-16 PF17851: GH43_C2" amino acids 352 to 550 (199 residues), 152.1 bits, see alignment E=1.7e-48

Best Hits

KEGG orthology group: K01198, xylan 1,4-beta-xylosidase [EC: 3.2.1.37] (inferred from 92% identity to pwa:Pecwa_2504)

Predicted SEED Role

"Beta-xylosidase (EC 3.2.1.37)" in subsystem Xylose utilization (EC 3.2.1.37)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.37

Use Curated BLAST to search for 3.2.1.37

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (558 amino acids)

>HER17_RS10220 glycoside hydrolase family 43 protein (Pectobacterium carotovorum WPP14)
MINNPIFKGFNPDPSICRRNNDYYVAVSSFEWFPGMPIYHSTDLKNWTLHTHVLRDEKKV
DLTRLPSAKGIWAPCLTWCEEKQLFYVIYGVMNSMHGRYFDVDNYLITAPEITGPWSEPV
YLHSGGYDASILHDEDGRKWIVAVDWETRDGHNGAISLVEYSPETRSVIGYPKRIWSGMT
GIGAEGPHLTKRGRYYYLMCAEGGTGYGHCVTMARAEQVWGPYESDAGNPILTSVNPALF
EKNNAEYEKPDFSILGVKDYLRPECFNPEVKIQKAGHGSYVETPEGEVYLVHLCARPFRP
ELCCPLGRESGIQKMRWTADGWMRLEGDDNIAKEVVEPSALPESPSFAPPVRDHFDDDTL
ALHYYAPRIHPDSFTDLHRRASHVCLRGQESLSSTNKVSLLARKLTSVYTTVKTKIHFTP
EVFQHSAGLVLYYDNMNYLYLQKHYDEENQCAALSVIHMENGAKREDWQGSTRLNADAVY
LRMTIEGRAISFAWSYDDVHYQAVGKVYETIKFSDEYSQHGEFTGTFVGIACVDSVLHQH
AAAFDFFDYQADETRDVE