Protein Info for HER17_RS09640 in Pectobacterium carotovorum WPP14

Annotation: PAS domain-containing methyl-accepting chemotaxis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 517 transmembrane" amino acids 172 to 190 (19 residues), see Phobius details amino acids 194 to 214 (21 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 20 to 113 (94 residues), 44.2 bits, see alignment E=1e-15 PF00989: PAS" amino acids 22 to 111 (90 residues), 27 bits, see alignment E=1.2e-09 PF08448: PAS_4" amino acids 23 to 112 (90 residues), 24.1 bits, see alignment E=1e-08 PF13426: PAS_9" amino acids 23 to 110 (88 residues), 37.1 bits, see alignment E=9.7e-13 PF08447: PAS_3" amino acids 31 to 106 (76 residues), 53.5 bits, see alignment E=7.1e-18 PF00672: HAMP" amino acids 211 to 257 (47 residues), 27.3 bits, see alignment 1.1e-09 PF00015: MCPsignal" amino acids 331 to 482 (152 residues), 147.7 bits, see alignment E=9.4e-47

Best Hits

KEGG orthology group: K03776, aerotaxis receptor (inferred from 98% identity to eca:ECA2002)

Predicted SEED Role

"Aerotaxis sensor receptor protein" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (517 amino acids)

>HER17_RS09640 PAS domain-containing methyl-accepting chemotaxis protein (Pectobacterium carotovorum WPP14)
MRNNTPVTDRQLPLSEKTRLMSVTTPESHITYANKDFIDVSGYTTDELMGQPHNLIRHPD
MPPAAFADMWKTLRAGNIWTGIVKNRCKNGDHYWVKSSTTPLRKGGEIAGYMSVRTAASP
EEIHQAEALYASANEGKLKYRTFHHGLLIYTGPLRILSLFKTMPLRWRIRSYFLLFSLIP
LIAAYSLLAGTALASVLFPLLIACCFVSGELLVHHVARPIEQILAQAMRSAAGQADNLTQ
LNRVDEIGMLMRAVNQSGMNFRTFVDDVNTNLSELKNACNEIAQGNHTLAQCCEETEESL
QQTAASVEQLTATIKSNAEASLQASLYTQDVNQAVNSGEQAVSQVSDTMETITRSSERIT
DIVSVMDNLAFQTNILAVNAAVEAAHAGEQGKSFAVVASEVRSLAQRSASSSSDISTIID
ETLNSIRTGEQQVSHTHKSMSNILLQVQHVTNLMNEISLATQEQSQGLEQINEAVNRIDE
LTHQNTALASQSHSATDHLQQQISSMVQAASVFSLSR