Protein Info for HER17_RS09530 in Pectobacterium carotovorum WPP14

Annotation: envelope stress response membrane protein PspC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 121 transmembrane" amino acids 36 to 63 (28 residues), see Phobius details TIGR02978: phage shock protein C" amino acids 8 to 121 (114 residues), 140.5 bits, see alignment E=1.2e-45 PF04024: PspC" amino acids 8 to 66 (59 residues), 63.2 bits, see alignment E=7.8e-22

Best Hits

Swiss-Prot: 62% identical to PSPC_ECOL6: Phage shock protein C (pspC) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K03973, phage shock protein C (inferred from 91% identity to pwa:Pecwa_2608)

Predicted SEED Role

"Phage shock protein C"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (121 amino acids)

>HER17_RS09530 envelope stress response membrane protein PspC (Pectobacterium carotovorum WPP14)
MKNTWSGKKLYRLPEEGMLKGVCAGLARYFDVPVKLVRLITVLSIFFGLFFFTVVAYIIL
TFMLDPAPAGMEFEDEKTARTPSQLLNEADATLQASEQRLRNIERYVTSDTFGVQNRFRH
L