Protein Info for HER17_RS09210 in Pectobacterium carotovorum WPP14

Annotation: urea carboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1201 PF00289: Biotin_carb_N" amino acids 1 to 109 (109 residues), 144.9 bits, see alignment E=4.4e-46 TIGR02712: urea carboxylase" amino acids 2 to 1197 (1196 residues), 1850.7 bits, see alignment E=0 PF02786: CPSase_L_D2" amino acids 116 to 319 (204 residues), 207.5 bits, see alignment E=6.4e-65 PF07478: Dala_Dala_lig_C" amino acids 139 to 291 (153 residues), 42.9 bits, see alignment E=1.5e-14 PF02785: Biotin_carb_C" amino acids 338 to 446 (109 residues), 105.5 bits, see alignment E=5.6e-34 TIGR00724: biotin-dependent carboxylase uncharacterized domain" amino acids 455 to 773 (319 residues), 287.4 bits, see alignment E=1.2e-89 PF02626: CT_A_B" amino acids 478 to 750 (273 residues), 318 bits, see alignment E=2e-98 PF02682: CT_C_D" amino acids 801 to 1018 (218 residues), 145.3 bits, see alignment E=7.3e-46 PF00364: Biotin_lipoyl" amino acids 1137 to 1196 (60 residues), 49 bits, see alignment 1.5e-16

Best Hits

Predicted SEED Role

"Urea carboxylase (EC 6.3.4.6)" in subsystem Urea decomposition (EC 6.3.4.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.3.4.6

Use Curated BLAST to search for 6.3.4.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1201 amino acids)

>HER17_RS09210 urea carboxylase (Pectobacterium carotovorum WPP14)
MFDKLLIANRGAIACRILRSLREMNVRGVAVYSDADISSLHIQDADEALSLGEGAAAHTY
LDVEKILSAAQRSGAQAIHPGYGFLSENAAFAEACEAAQIAFVGPTPQQLRVFGLKHTAR
ALAKQHNVPLLEGTELLENIDAALRAAEAIGYPVMLKSTAGGGGIGMRVCYSTTELSDAF
ETVKRLGQNNFSDAGVFIEKYIERARHLEVQIFGDGQGDVLALGVRDCSVQRRNQKVIEE
TPAPNLPDGVADALCAAAISLAQAVNYRSAGTVEFVYDSATDRFYFLEVNTRLQVEHGVT
EQVWGVDLVRWMIELAAGDLPPLHELAAGLNPQGHAIQARLYAEDPGKQFQPSPGLLTEV
VFPESEGQSLRIDTWVTAGCEIPPFFDPMLAKIIACAPTREQAIVGLDRALADTRLYGVE
HNRDYLRQILAAEPFASGQPWTRCLDTLVYNATTCEVVSAGTQTTVQDYPGRLGYWAVGV
PPSGPMDDRALRLGNRLVGNPAGMAALEITMNGPTLRFNTDAVAAVTGEAMAIELDGQPV
PMDSVFAIPAGATLRLGAANAQGVRSYLCLRGGFDVPDYLGSKSTFTLGQFGGHAGRALR
AGDVLHLAPLTDRRTGDCLPDALRTTLSAVRELRVIYGPHAAPDYFTPAYMETFLTTEWE
VHFNSSRTGVRLIGPKPEWVRDSGGEAGLHPSNIHDNPYAIGAVDFTGDMPVILGPDGPS
LGGFVCPVTIIEADLWSLGQLTAGDRVRFIPVDLPTARALAQARHAEVEQLAPIAVDWSP
AALISPVVLDSGEADKRLVARLSGDTHLLLEVGAAELDVALRFRVHALMLALEKQTLDGI
IDVTPGIRSLQVHYRPEVLSLQHLLDVLSTLWQDVCTQQNLTVPSRVVYLPLSWDDPACQ
LAIQKYMTTVRSDAPWCPSNLEFIRRINELDNLDEVYRTVFDASYLVMGLGDVYLGAPVA
TPLDPRHRLVTTKYNPARTWTAENSVGIGGAYLCVYGMEGPGGYQFVGRTLQMWDRYRGV
GAFDGKPWLLRFFDQIRFYPVSADELLSIRRDFPLGRYPLRIEQSELALNAYQDFLSREA
EEIEAFRVRQRAAFEAERERWRIAGQSVTDSVDVVIEEASEAPILPGQVGVESPISGNLW
QVTTEVGKTVAEGETLMILESMKMEIPIVSLQCGTVREIRCQPGASVRAGQCVVVIESQT
E