Protein Info for HER17_RS09160 in Pectobacterium carotovorum WPP14

Annotation: metallophosphoesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 421 transmembrane" amino acids 45 to 64 (20 residues), see Phobius details amino acids 76 to 94 (19 residues), see Phobius details amino acids 106 to 133 (28 residues), see Phobius details amino acids 149 to 168 (20 residues), see Phobius details PF00149: Metallophos" amino acids 193 to 360 (168 residues), 45.8 bits, see alignment E=5e-16

Best Hits

KEGG orthology group: K07098, (no description) (inferred from 94% identity to eca:ECA1908)

Predicted SEED Role

"putative membrane-attached phosphoesterase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (421 amino acids)

>HER17_RS09160 metallophosphoesterase (Pectobacterium carotovorum WPP14)
MELRHVNLHLLATQHLYRVDLQCVRHGVKFTRQYTDITDKERKTSVFHVITGLIALYVIW
RLVWRLRVGVPVKRMLAVLVLLASQHHLITRTFFGTMASPEVPAFVLMFLGWAFGALLIS
AFLLLAIDLLGIVGRLLSRSVGQTLLNNMALRGGMAVVAMGLAAIGVWEAVRVPEVRTVE
VELKQLPPALDGFRLVQLTDLHASRLLQRPWMEAVVAKTNALKPDLTVITGDLADGTVSA
RHDDMEPLRNLTAPHGVFAIVGNHEYYVEYTQWVQRLNALGLRMLLNENVSIGRDNAAFV
LAGITDRTAADFQQLLPDTAAALSGIAPDTAVVLLSHRPTGAKENARAGADLQLSGHTHG
GQVLGMHWVTQLANEGYVSGSYDVDGMHLYVSNGAGLWNGFPIRLGKRAEITQFILRSPS
L